Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer

Giannakopoulou, G; Spyrou, GM; Antaraki, A; Andreadis, I; Koulocheri, D; Zagouri, F; Nonni, A; Filippakis, GM; Nikita, KS; Ligomenides, PA; Zografos, GC

dc.contributor.author	Giannakopoulou, G	en
dc.contributor.author	Spyrou, GM	en
dc.contributor.author	Antaraki, A	en
dc.contributor.author	Andreadis, I	en
dc.contributor.author	Koulocheri, D	en
dc.contributor.author	Zagouri, F	en
dc.contributor.author	Nonni, A	en
dc.contributor.author	Filippakis, GM	en
dc.contributor.author	Nikita, KS	en
dc.contributor.author	Ligomenides, PA	en
dc.contributor.author	Zografos, GC	en
dc.date.accessioned	2014-03-01T01:33:10Z
dc.date.available	2014-03-01T01:33:10Z
dc.date.issued	2010	en
dc.identifier.issn	0010-4825	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/20358
dc.subject	BIRADS 3	en
dc.subject	CAD system	en
dc.subject	Early breast cancer	en
dc.subject	Microcalcifications	en
dc.subject	SVABB	en
dc.subject.classification	Biology	en
dc.subject.classification	Computer Science, Interdisciplinary Applications	en
dc.subject.classification	Engineering, Biomedical	en
dc.subject.classification	Mathematical & Computational Biology	en
dc.subject.other	BI-RADS	en
dc.subject.other	CAD system	en
dc.subject.other	Early breast cancer	en
dc.subject.other	Microcalcifications	en
dc.subject.other	SVABB	en
dc.subject.other	Biopsy	en
dc.subject.other	Computer aided analysis	en
dc.subject.other	Medical computing	en
dc.subject.other	Risk analysis	en
dc.subject.other	Risk assessment	en
dc.subject.other	Computer aided diagnosis	en
dc.subject.other	adult	en
dc.subject.other	aged	en
dc.subject.other	article	en
dc.subject.other	breast biopsy	en
dc.subject.other	breast cancer	en
dc.subject.other	cancer diagnosis	en
dc.subject.other	cancer grading	en
dc.subject.other	computer aided design	en
dc.subject.other	computer aided microcalcification analysis	en
dc.subject.other	early cancer	en
dc.subject.other	female	en
dc.subject.other	human	en
dc.subject.other	human tissue	en
dc.subject.other	major clinical study	en
dc.subject.other	mammography	en
dc.subject.other	priority journal	en
dc.subject.other	risk assessment	en
dc.subject.other	Adult	en
dc.subject.other	Aged	en
dc.subject.other	Aged, 80 and over	en
dc.subject.other	Biopsy	en
dc.subject.other	Breast Neoplasms	en
dc.subject.other	Calcinosis	en
dc.subject.other	Diagnosis, Computer-Assisted	en
dc.subject.other	Female	en
dc.subject.other	Humans	en
dc.subject.other	Mammography	en
dc.subject.other	Middle Aged	en
dc.subject.other	Risk Assessment	en
dc.title	Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/j.compbiomed.2010.09.005	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.compbiomed.2010.09.005	en
heal.language	English	en
heal.publicationDate	2010	en
heal.abstract	This paper explores the potential of a computer-aided diagnosis system to discriminate the real benign microcalcifications among a specific subset of 109 patients with BIRADS 3 mammograms who had undergone biopsy, thus making it possible to downgrade them to BIRADS 2 category. The system detected and quantified critical features of microcalcifications and classified them on a risk percentage scale for malignancy. The system successfully detected all cancers. Nevertheless, it suggested biopsy for 11/15 atypical lesions. Finally, the system characterized as definitely benign (BIRADS 2) 29/88 benign lesions, previously assigned to BIRADS 3. and thus achieved a reduction of 33% in unnecessary biopsies. (C) 2010 Elsevier Ltd. All rights reserved.	en
heal.publisher	PERGAMON-ELSEVIER SCIENCE LTD	en
heal.journalName	Computers in Biology and Medicine	en
dc.identifier.doi	10.1016/j.compbiomed.2010.09.005	en
dc.identifier.isi	ISI:000285174700003	en
dc.identifier.volume	40	en
dc.identifier.issue	11-12	en
dc.identifier.spage	853	en
dc.identifier.epage	859	en