Principal component analysis of the P600 waveform: RF and gender effects

Maganioti, AE; Hountala, CD; Papageorgiou, CC; Kyprianou, MA; Rabavilas, AD; Capsalis, CN

dc.contributor.author	Maganioti, AE	en
dc.contributor.author	Hountala, CD	en
dc.contributor.author	Papageorgiou, CC	en
dc.contributor.author	Kyprianou, MA	en
dc.contributor.author	Rabavilas, AD	en
dc.contributor.author	Capsalis, CN	en
dc.date.accessioned	2014-03-01T01:34:21Z
dc.date.available	2014-03-01T01:34:21Z
dc.date.issued	2010	en
dc.identifier.issn	0304-3940	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/20706
dc.subject	Activation pattern	en
dc.subject	Gender	en
dc.subject	Mobile phone	en
dc.subject	P600	en
dc.subject	PCA	en
dc.subject	Radiofrequency	en
dc.subject.classification	Neurosciences	en
dc.subject.other	adult	en
dc.subject.other	amplitude modulation	en
dc.subject.other	analysis of variance	en
dc.subject.other	article	en
dc.subject.other	auditory memory	en
dc.subject.other	brain region	en
dc.subject.other	controlled study	en
dc.subject.other	electrode	en
dc.subject.other	event related potential	en
dc.subject.other	female	en
dc.subject.other	human	en
dc.subject.other	human experiment	en
dc.subject.other	latent period	en
dc.subject.other	male	en
dc.subject.other	mobile phone	en
dc.subject.other	normal human	en
dc.subject.other	principal component analysis	en
dc.subject.other	priority journal	en
dc.subject.other	radiofrequency	en
dc.subject.other	sex difference	en
dc.subject.other	task performance	en
dc.subject.other	Acoustic Stimulation	en
dc.subject.other	Adult	en
dc.subject.other	Cellular Phone	en
dc.subject.other	Electroencephalography	en
dc.subject.other	Electromagnetic Fields	en
dc.subject.other	Evoked Potentials, Auditory	en
dc.subject.other	Female	en
dc.subject.other	Humans	en
dc.subject.other	Male	en
dc.subject.other	Mental Recall	en
dc.subject.other	Principal Component Analysis	en
dc.subject.other	Sex Factors	en
dc.subject.other	Speech Perception	en
dc.subject.other	Young Adult	en
dc.title	Principal component analysis of the P600 waveform: RF and gender effects	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/j.neulet.2010.04.058	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.neulet.2010.04.058	en
heal.language	English	en
heal.publicationDate	2010	en
heal.abstract	The aim of the present study was to examine the patterns of activation of the P600 waveform of the event-related potentials (ERP), applying principal component analysis (PCA) and repeated measures ANOVA, and whether these patterns are RF and gender dependent. The ERPs of thirty-nine healthy subjects (20 male and 19 female) were recorded during an auditory memory task in the presence and absence of RF, similar to that emitted by mobile phones. Both PCA and ANOVA produced congruent results, showing that activation of the P600 component occurs early and more intensely in the region of the posterior electrodes and in a less intense manner in the central electrodes. Conversely, the activation at the anterior electrodes arises later with a considerably reduced intensity. In the absence of RF female subjects exhibited significantly lower amplitudes at anterior electrodes and earlier latencies at central electrodes than male subjects. These differences disappear in the presence of RF. Consequently, the P600 component follows distinct patterns of activation in the anterior, central and posterior brain areas and gender differences are observed simultaneously at several electrodes within these areas. Finally, the gender-related functional architecture with regard the P600 component appears to be RF sensitive. In conclusion, the application of the PCA procedure provides an adequate model of the spatially distributed event-related dynamics that correspond to the P600 waveform. (C) 2010 Elsevier Ireland Ltd. All rights reserved.	en
heal.publisher	ELSEVIER IRELAND LTD	en
heal.journalName	Neuroscience Letters	en
dc.identifier.doi	10.1016/j.neulet.2010.04.058	en
dc.identifier.isi	ISI:000279164600005	en
dc.identifier.volume	478	en
dc.identifier.issue	1	en
dc.identifier.spage	19	en
dc.identifier.epage	23	en