Covalent attachment of a bioactive hyperbranched polymeric layer to titanium surface for the biomimetic growth of calcium phosphates

Tsiourvas, D; Tsetsekou, A; Arkas, M; Diplas, S; Mastrogianni, E

dc.contributor.author	Tsiourvas, D	en
dc.contributor.author	Tsetsekou, A	en
dc.contributor.author	Arkas, M	en
dc.contributor.author	Diplas, S	en
dc.contributor.author	Mastrogianni, E	en
dc.date.accessioned	2014-03-01T01:35:28Z
dc.date.available	2014-03-01T01:35:28Z
dc.date.issued	2011	en
dc.identifier.issn	0957-4530	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/21064
dc.subject	Calcium Phosphate	en
dc.subject	Hydroxyapatite	en
dc.subject	Surface Morphology	en
dc.subject	Titanium	en
dc.subject	Poly Ethylene Imine	en
dc.subject	Simulated Body Fluid	en
dc.subject.classification	Engineering, Biomedical	en
dc.subject.classification	Materials Science, Biomaterials	en
dc.subject.other	Biomimetic growth	en
dc.subject.other	Calcium phosphate formation	en
dc.subject.other	Chemical grafting	en
dc.subject.other	Chemical pre-treatment	en
dc.subject.other	Coating layer	en
dc.subject.other	Covalent attachment	en
dc.subject.other	Deposition stages	en
dc.subject.other	FTIR	en
dc.subject.other	Hybrid layer	en
dc.subject.other	Hyperbranched	en
dc.subject.other	Organosilicones	en
dc.subject.other	Poly(ethyleneimine)	en
dc.subject.other	Polymeric layers	en
dc.subject.other	Reaction conditions	en
dc.subject.other	Reaction steps	en
dc.subject.other	SEM	en
dc.subject.other	Simulated body fluids	en
dc.subject.other	Surface silanization	en
dc.subject.other	Titanium surfaces	en
dc.subject.other	XPS analysis	en
dc.subject.other	Biomaterials	en
dc.subject.other	Biomimetics	en
dc.subject.other	Calcium phosphate	en
dc.subject.other	Ethylene	en
dc.subject.other	Functional polymers	en
dc.subject.other	Grafts	en
dc.subject.other	Hydroxyapatite	en
dc.subject.other	Nitrogen compounds	en
dc.subject.other	Phosphate coatings	en
dc.subject.other	Polymers	en
dc.subject.other	Protective coatings	en
dc.subject.other	Reaction intermediates	en
dc.subject.other	Surface morphology	en
dc.subject.other	Surface reactions	en
dc.subject.other	Titanium	en
dc.subject.other	Grafting (chemical)	en
dc.subject.other	biomimetic material	en
dc.subject.other	calcium phosphate	en
dc.subject.other	hydroxyapatite	en
dc.subject.other	polyethyleneimine	en
dc.subject.other	titanium	en
dc.subject.other	article	en
dc.subject.other	body fluid	en
dc.subject.other	controlled study	en
dc.subject.other	infrared spectroscopy	en
dc.subject.other	material coating	en
dc.subject.other	priority journal	en
dc.subject.other	scanning electron microscopy	en
dc.subject.other	simulation	en
dc.subject.other	X ray photoelectron spectroscopy	en
dc.subject.other	Biomimetic Materials	en
dc.subject.other	Body Fluids	en
dc.subject.other	Calcium Phosphates	en
dc.subject.other	Coated Materials, Biocompatible	en
dc.subject.other	Crystallization	en
dc.subject.other	Hydrogen Bonding	en
dc.subject.other	Materials Testing	en
dc.subject.other	Microscopy, Electron, Scanning	en
dc.subject.other	Models, Biological	en
dc.subject.other	Polyethyleneimine	en
dc.subject.other	Polymers	en
dc.subject.other	Spectrometry, X-Ray Emission	en
dc.subject.other	Spectroscopy, Fourier Transform Infrared	en
dc.subject.other	Surface Properties	en
dc.subject.other	Titanium	en
dc.title	Covalent attachment of a bioactive hyperbranched polymeric layer to titanium surface for the biomimetic growth of calcium phosphates	en
heal.type	journalArticle	en
heal.identifier.primary	10.1007/s10856-010-4181-7	en
heal.identifier.secondary	http://dx.doi.org/10.1007/s10856-010-4181-7	en
heal.language	English	en
heal.publicationDate	2011	en
heal.abstract	This work is investigating the chemical grafting on Ti surface of a polymer/calcium phosphate coating of improved adhesion for enhanced bioactivity. For this purpose, a whole new methodology was developed based on covalently attaching a hyperbranched poly(ethylene imine) layer on Ti surface able to promote calcium phosphate formation in a next deposition stage. This was achieved through an intermediate surface silanization step. The research included optimization both of the reaction conditions for covalently grafting the intermediate organosilicon and the subsequent hyperbranched poly(ethylene imine) layers, as well as of the conditions for the mechanical and chemical pretreatment of Ti surface before coating. The reaction steps were monitored employing FTIR and XPS analyses, whereas the surface morphology and structure of the successive coating layers were studied by SEM combined with EDS. The analysis confirmed the successful grafting of the hybrid layer which demonstrated very good ability for hydroxyapatite growth in simulated body fluid. © 2010 The Author(s).	en
heal.publisher	SPRINGER	en
heal.journalName	Journal of Materials Science: Materials in Medicine	en
dc.identifier.doi	10.1007/s10856-010-4181-7	en
dc.identifier.isi	ISI:000288516300009	en
dc.identifier.volume	22	en
dc.identifier.issue	1	en
dc.identifier.spage	85	en
dc.identifier.epage	96	en