Effect of ketogenic mediterranean diet with phytoextracts and low carbohydrates/high-protein meals on weight, cardiovascular risk factors, body composition and diet compliance in Italian council employees

Paoli, A; Cenci, L; Grimaldi, KA

dc.contributor.author	Paoli, A	en
dc.contributor.author	Cenci, L	en
dc.contributor.author	Grimaldi, KA	en
dc.date.accessioned	2014-03-01T01:35:35Z
dc.date.available	2014-03-01T01:35:35Z
dc.date.issued	2011	en
dc.identifier.issn	1475-2891	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/21113
dc.subject.classification	Nutrition & Dietetics	en
dc.subject.other	alpha tocopherol	en
dc.subject.other	ascorbic acid	en
dc.subject.other	beta carotene	en
dc.subject.other	biotin	en
dc.subject.other	calcium	en
dc.subject.other	carbohydrate	en
dc.subject.other	cholesterol	en
dc.subject.other	chromium	en
dc.subject.other	colecalciferol	en
dc.subject.other	copper	en
dc.subject.other	folic acid	en
dc.subject.other	glucose	en
dc.subject.other	high density lipoprotein cholesterol	en
dc.subject.other	iron	en
dc.subject.other	low density lipoprotein cholesterol	en
dc.subject.other	magnesium	en
dc.subject.other	manganese	en
dc.subject.other	multivitaminico balestra	en
dc.subject.other	nicotinic acid	en
dc.subject.other	olive oil	en
dc.subject.other	pantothenic acid	en
dc.subject.other	phosphorus	en
dc.subject.other	plant extract	en
dc.subject.other	potassium	en
dc.subject.other	pyridoxine	en
dc.subject.other	riboflavin	en
dc.subject.other	selenium	en
dc.subject.other	thiamine	en
dc.subject.other	tisanoreica	en
dc.subject.other	triacylglycerol	en
dc.subject.other	unclassified drug	en
dc.subject.other	unindexed drug	en
dc.subject.other	zinc	en
dc.subject.other	adult	en
dc.subject.other	article	en
dc.subject.other	body composition	en
dc.subject.other	body mass	en
dc.subject.other	body weight	en
dc.subject.other	cardiovascular risk	en
dc.subject.other	cheese	en
dc.subject.other	cholesterol blood level	en
dc.subject.other	employee	en
dc.subject.other	female	en
dc.subject.other	fish	en
dc.subject.other	glucose blood level	en
dc.subject.other	human	en
dc.subject.other	Italy	en
dc.subject.other	ketogenic diet	en
dc.subject.other	leafy vegetable	en
dc.subject.other	low carbohydrate diet	en
dc.subject.other	major clinical study	en
dc.subject.other	male	en
dc.subject.other	meat	en
dc.subject.other	Mediterranean diet	en
dc.subject.other	obesity	en
dc.subject.other	pilot study	en
dc.subject.other	protein diet	en
dc.subject.other	triacylglycerol blood level	en
dc.subject.other	waist circumference	en
dc.subject.other	weight reduction	en
dc.title	Effect of ketogenic mediterranean diet with phytoextracts and low carbohydrates/high-protein meals on weight, cardiovascular risk factors, body composition and diet compliance in Italian council employees	en
heal.type	journalArticle	en
heal.identifier.primary	10.1186/1475-2891-10-112	en
heal.identifier.secondary	http://dx.doi.org/10.1186/1475-2891-10-112	en
heal.identifier.secondary	112	en
heal.language	English	en
heal.publicationDate	2011	en
heal.abstract	Background: There has been increased interest in recent years in very low carbohydrate ketogenic diets (VLCKD) that, even though they are much discussed and often opposed, have undoubtedly been shown to be effective, at least in the short to medium term, as a tool to tackle obesity, hyperlipidemia and some cardiovascular risk factors. For this reason the ketogenic diet represents an interesting option but unfortunately suffers from a low compliance. The aim of this pilot study is to ascertain the safety and effects of a modified ketogenic diet that utilizes ingredients which are low in carbohydrates but are formulated to simulate its aspect and taste and also contain phytoextracts to add beneficial effects of important vegetable components. Methods. The study group consisted of 106 Rome council employees with a body mass index of 25, age between 18 and 65 years (19 male and 87 female; mean age 48.49 10.3). We investigated the effects of a modified ketogenic diet based on green vegetables, olive oil, fish and meat plus dishes composed of high quality protein and virtually zero carbohydrate but which mimic their taste, with the addition of some herbal extracts (KEMEPHY ketogenic Mediterranean with phytoextracts). Calories in the diet were unlimited. Measurements were taken before and after 6 weeks of diet. Results: There were no significant changes in BUN, ALT, AST, GGT and blood creatinine. We detected a significant (p < 0.0001) reduction in BMI (31.45 Kg/m2 to 29.01 Kg/m2), body weight (86.15 kg to 79.43 Kg), percentage of fat mass (41.24% to 34.99%), waist circumference (106.56 cm to 97.10 cm), total cholesterol (204 mg/dl to 181 mg/dl), LDLc (150 mg/dl to 136 mg/dl), triglycerides (119 mg/dl to 93 mg/dl) and blood glucose (96 mg/dl to 91 mg/dl). There was a significant (p < 0.0001) increase in HDLc (46 mg/dl to 52 mg/dl). Conclusions: The KEMEPHY diet lead to weight reduction, improvements in cardiovascular risk markers, reduction in waist circumference and showed good compliance. © 2011 Paoli et al; licensee BioMed Central Ltd.	en
heal.publisher	BIOMED CENTRAL LTD	en
heal.journalName	Nutrition Journal	en
dc.identifier.doi	10.1186/1475-2891-10-112	en
dc.identifier.isi	ISI:000297102500001	en
dc.identifier.volume	10	en
dc.identifier.issue	1	en