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Serratia infections in a general hospital: Characteristics and outcomes

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dc.contributor.author Samonis, G en
dc.contributor.author Vouloumanou, EK en
dc.contributor.author Christofaki, M en
dc.contributor.author Dimopoulou, D en
dc.contributor.author Maraki, S en
dc.contributor.author Triantafyllou, E en
dc.contributor.author Kofteridis, DP en
dc.contributor.author Falagas, ME en
dc.date.accessioned 2014-03-01T01:37:04Z
dc.date.available 2014-03-01T01:37:04Z
dc.date.issued 2011 en
dc.identifier.issn 0934-9723 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/21434
dc.subject.classification Infectious Diseases en
dc.subject.classification Microbiology en
dc.subject.other amikacin en
dc.subject.other amoxicillin plus clavulanic acid en
dc.subject.other ampicillin en
dc.subject.other aztreonam en
dc.subject.other beta lactamase inhibitor en
dc.subject.other carbapenem derivative en
dc.subject.other cefalotin en
dc.subject.other cefotaxime en
dc.subject.other cefoxitin en
dc.subject.other ceftazidime en
dc.subject.other ceftriaxone en
dc.subject.other cefuroxime en
dc.subject.other chloramphenicol en
dc.subject.other cotrimoxazole en
dc.subject.other gentamicin en
dc.subject.other imipenem en
dc.subject.other meropenem en
dc.subject.other nalidixic acid en
dc.subject.other netilmicin en
dc.subject.other nitrofurantoin en
dc.subject.other penicillin derivative en
dc.subject.other piperacillin en
dc.subject.other piperacillin plus tazobactam en
dc.subject.other quinoline derived antiinfective agent en
dc.subject.other tetracycline en
dc.subject.other ticarcillin en
dc.subject.other timentin en
dc.subject.other tobramycin en
dc.subject.other trimethoprim en
dc.subject.other unindexed drug en
dc.subject.other adult en
dc.subject.other antibacterial activity en
dc.subject.other antibiotic resistance en
dc.subject.other antibiotic sensitivity en
dc.subject.other article en
dc.subject.other bacterium isolate en
dc.subject.other cause of death en
dc.subject.other controlled study en
dc.subject.other endophthalmitis en
dc.subject.other female en
dc.subject.other general hospital en
dc.subject.other hospital infection en
dc.subject.other human en
dc.subject.other infant en
dc.subject.other keratitis en
dc.subject.other major clinical study en
dc.subject.other male en
dc.subject.other mortality en
dc.subject.other nonhuman en
dc.subject.other outcome assessment en
dc.subject.other outpatient en
dc.subject.other priority journal en
dc.subject.other respiratory tract infection en
dc.subject.other retrospective study en
dc.subject.other Serratia infection en
dc.subject.other Serratia marcescens en
dc.subject.other Adult en
dc.subject.other Aged en
dc.subject.other Aged, 80 and over en
dc.subject.other Anti-Bacterial Agents en
dc.subject.other Cross Infection en
dc.subject.other Endophthalmitis en
dc.subject.other Greece en
dc.subject.other Hospitals, General en
dc.subject.other Humans en
dc.subject.other Keratitis en
dc.subject.other Male en
dc.subject.other Microbial Sensitivity Tests en
dc.subject.other Middle Aged en
dc.subject.other Respiratory Tract Infections en
dc.subject.other Retrospective Studies en
dc.subject.other Serratia Infections en
dc.subject.other Serratia marcescens en
dc.subject.other Treatment Outcome en
dc.title Serratia infections in a general hospital: Characteristics and outcomes en
heal.type journalArticle en
heal.identifier.primary 10.1007/s10096-010-1135-4 en
heal.identifier.secondary http://dx.doi.org/10.1007/s10096-010-1135-4 en
heal.language English en
heal.publicationDate 2011 en
heal.abstract We aimed to present our experience regarding infections caused by Serratia spp. in a region with relatively high antimicrobial resistance rates. We retrospectively reviewed the databases of the microbiological laboratory of the University Hospital of Heraklion, Crete (2/2004-12/2009). A total of 77 patients [67.5% men, mean age ± standard deviation (SD)=56.9±24.5 years) were identified; 37.7% were outpatients. Sixty-five (84.4%) of the 77 included patients had a Serratia marcescens isolate; the remaining 12 patients had a non-marcescens Serratia spp. The most frequently observed infections were respiratory tract infection (32.5%) and keratitis/endophthalmitis (20.8%). Seventy-three (94.9%) patients were cured. Four deaths were observed; three of them were considered as attributed to the Serratia infection. No difference was found regarding the characteristics and outcomes between patients with Serratia marcescens and non-marcescens infections. In addition, antipseudomonal penicillins and their combinations with beta-lactamase inhibitors, as well as carbapenemes, and fluoroquinolones exhibited high antimicrobial activity against both the tested Serratia marcescens and non-marcescens isolates. Our study adds useful information regarding the characteristics and outcomes of patients with Serratia infection, as well as the susceptibilities of the respective Serratia marcescens and non-marcescens isolates, in a region with relatively high levels of antimicrobial resistance. © 2011 Springer-Verlag. en
heal.publisher SPRINGER en
heal.journalName European Journal of Clinical Microbiology and Infectious Diseases en
dc.identifier.doi 10.1007/s10096-010-1135-4 en
dc.identifier.isi ISI:000289483300007 en
dc.identifier.volume 30 en
dc.identifier.issue 5 en
dc.identifier.spage 653 en
dc.identifier.epage 660 en


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