Toxicity tolerance of Fusarium oxysporum towards inhibitory compounds formed during pretreatment of lignocellulosic materials

Xiros, C; Vafiadi, C; Paschos, T; Christakopoulos, P

dc.contributor.author	Xiros, C	en
dc.contributor.author	Vafiadi, C	en
dc.contributor.author	Paschos, T	en
dc.contributor.author	Christakopoulos, P	en
dc.date.accessioned	2014-03-01T01:37:29Z
dc.date.available	2014-03-01T01:37:29Z
dc.date.issued	2011	en
dc.identifier.issn	0268-2575	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/21524
dc.subject	Fermentation	en
dc.subject	Lignocellulosic hydrolyzates	en
dc.subject	Pre-treatment	en
dc.subject	Toxicity	en
dc.subject.classification	Biotechnology & Applied Microbiology	en
dc.subject.classification	Chemistry, Multidisciplinary	en
dc.subject.classification	Engineering, Chemical	en
dc.subject.other	Aerobic growth	en
dc.subject.other	Bioconversion process	en
dc.subject.other	Biomass productions	en
dc.subject.other	Ethanol fermentation	en
dc.subject.other	Ethanol production	en
dc.subject.other	Furan derivatives	en
dc.subject.other	Fusarium oxysporums	en
dc.subject.other	Growth stages	en
dc.subject.other	High concentration	en
dc.subject.other	Individual models	en
dc.subject.other	Inhibitory compounds	en
dc.subject.other	Lag phase	en
dc.subject.other	Lignocellulosic hydrolyzates	en
dc.subject.other	Lignocellulosic material	en
dc.subject.other	Phenolic compounds	en
dc.subject.other	Pre-Treatment	en
dc.subject.other	Specific growth rate	en
dc.subject.other	Tolerance levels	en
dc.subject.other	Weak organic acids	en
dc.subject.other	Bioethanol	en
dc.subject.other	Carboxylic acids	en
dc.subject.other	Ecology	en
dc.subject.other	Ethanol	en
dc.subject.other	Fermentation	en
dc.subject.other	Organic acids	en
dc.subject.other	Phenols	en
dc.subject.other	Toxicity	en
dc.subject.other	Growth (materials)	en
dc.subject.other	2 furoic acid	en
dc.subject.other	acetic acid	en
dc.subject.other	acetosyringone	en
dc.subject.other	carboxylic acid	en
dc.subject.other	formic acid	en
dc.subject.other	furfural	en
dc.subject.other	guaiacol	en
dc.subject.other	lignocellulose	en
dc.subject.other	phenol	en
dc.subject.other	vanillic acid	en
dc.subject.other	alcohol production	en
dc.subject.other	anaerobic fermentation	en
dc.subject.other	article	en
dc.subject.other	biomass production	en
dc.subject.other	biotransformation	en
dc.subject.other	clinical evaluation	en
dc.subject.other	controlled study	en
dc.subject.other	fermentation	en
dc.subject.other	fungus growth	en
dc.subject.other	Fusarium oxysporum	en
dc.subject.other	nonhuman	en
dc.subject.other	Fungi	en
dc.subject.other	Fusarium oxysporum	en
dc.title	Toxicity tolerance of Fusarium oxysporum towards inhibitory compounds formed during pretreatment of lignocellulosic materials	en
heal.type	journalArticle	en
heal.identifier.primary	10.1002/jctb.2499	en
heal.identifier.secondary	http://dx.doi.org/10.1002/jctb.2499	en
heal.language	English	en
heal.publicationDate	2011	en
heal.abstract	BACKGROUND: During the pretreatment of lignocellulosic materials, molecules such as carboxylic acids, furan derivatives and phenolic compounds, which inhibit the growth and ethanol fermentation by bacteria, fungi and yeasts, are produced. The present work determines the tolerance levels of the C5, C6 fermenting fungus Fusarium oxysporum, towards individual model inhibitory compounds on aerobic growth, on lignocellulolytic activities and on fermentative performance. RESULTS: During the growth stage, maximum biomass production was more affected than the specific growth rate by the presence of inhibitors. The presence of high concentrations of inhibitors resulted, in most cases, in prolongation of the lag phase. The fermentative performance of F. oxysporum was significantly inhibited by carboxylic acids, while the lignocellulolytic activities were affected to a lesser extent. CONCLUSION: The toxicity tolerance of F. oxysporum was high enough for aerobic growth in the presence of significant concentrations of inhibitors, which in most cases were higher than those generated from various treatments of lignocellulosic materials, while its fermentative performance was relatively more affected by the presence of inhibitors. The decrease of ethanol production in the presence of weak organic acids could be the main obstacle to the application of F. oxysporum in large-scale bioconversion processes of hydrolysates containing inhibitors. (C) 2010 Society of Chemical Industry	en
heal.publisher	JOHN WILEY & SONS LTD	en
heal.journalName	Journal of Chemical Technology and Biotechnology	en
dc.identifier.doi	10.1002/jctb.2499	en
dc.identifier.isi	ISI:000286852200008	en
dc.identifier.volume	86	en
dc.identifier.issue	2	en
dc.identifier.spage	223	en
dc.identifier.epage	230	en