Synthesis of a protected octapeptide analogue of hypertensin II

Theodoropoulos, D

dc.contributor.author	Theodoropoulos, D	en
dc.date.accessioned	2014-03-01T01:37:39Z
dc.date.available	2014-03-01T01:37:39Z
dc.date.issued	1962	en
dc.identifier.issn	00280836	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/21588
dc.title	Synthesis of a protected octapeptide analogue of hypertensin II	en
heal.type	journalArticle	en
heal.identifier.primary	10.1038/194283b0	en
heal.identifier.secondary	http://dx.doi.org/10.1038/194283b0	en
heal.publicationDate	1962	en
heal.abstract	IN order to investigate whether the basicity of the amino-acid residue at position 2 in hypertensin II has any strong bearing on its biological activity or affects the balance of oxytocic and pressor properties of this hormone, the histidine1-hypertensin analogue2 was synthesized in this laboratory. I used the procedure for histidyl peptides1, which also leads to the synthesis of the im. benzyl analogue. The latter might spread light on the biological significance of the imidazole ring of histidine. © 1962 Nature Publishing Group.	en
heal.journalName	Nature	en
dc.identifier.doi	10.1038/194283b0	en
dc.identifier.volume	194	en
dc.identifier.issue	4825	en
dc.identifier.spage	283	en
dc.identifier.epage	284	en