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Synthesis of 2-substituted 3(2H)-isothiazolones from 2-substituted 5-aroyl-3(2H)-isothiazolones

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dc.contributor.author Tsolomitis, A en
dc.contributor.author Sandris, C en
dc.date.accessioned 2014-03-01T01:39:14Z
dc.date.available 2014-03-01T01:39:14Z
dc.date.issued 1987 en
dc.identifier.issn 03855414 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/22637
dc.relation.uri http://www.scopus.com/inward/record.url?eid=2-s2.0-0001179080&partnerID=40&md5=6516ea1458f8d0df3e77ac1149eef035 en
dc.title Synthesis of 2-substituted 3(2H)-isothiazolones from 2-substituted 5-aroyl-3(2H)-isothiazolones en
heal.type journalArticle en
heal.publicationDate 1987 en
heal.abstract 2-Substituted 3(2H)-isothiazolones 3 have been prepared from 2-substituted 5-aroyl-3(2H)-isothiazolones 6, which are readily available from N-substituted 3-aroylpropionamides 5. The nucleophilic displacement on the 5-aroyl group was found to proceed easily and quantitatively when a benzene solution of compound 6 was stirred at room temperature either with a 10% sodium hydroxide solution or with solid sodium hydroxide. © 1987. en
heal.journalName Heterocycles en
dc.identifier.volume 25 en
dc.identifier.issue C en
dc.identifier.spage 569 en
dc.identifier.epage 575 en


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