Novel Structural Features of the Human Histocompatibility Molecules HLA-DQ as Revealed by Modeling Based on the Published Structure of the Related Molecule HLA-DR

Papadopoulos, G

dc.contributor.author	Papadopoulos, G	en
dc.date.accessioned	2014-03-01T01:44:26Z
dc.date.available	2014-03-01T01:44:26Z
dc.date.issued	1996	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/24373
dc.subject	Antigen Presenting Cell	en
dc.subject	Autoimmune Disease	en
dc.subject	Cell Adhesion	en
dc.subject	Polymorphism	en
dc.subject	Structural Model	en
dc.subject	T Lymphocyte	en
dc.title	Novel Structural Features of the Human Histocompatibility Molecules HLA-DQ as Revealed by Modeling Based on the Published Structure of the Related Molecule HLA-DR	en
heal.type	journalArticle	en
heal.identifier.primary	10.1006/jsbi.1996.0079	en
heal.identifier.secondary	http://dx.doi.org/10.1006/jsbi.1996.0079	en
heal.publicationDate	1996	en
heal.abstract	Structural modeling of the HLA-DQ molecules, a group of human histocompatibility antigens linked to autoimmune diseases and immunosuppression-based on the structure of the homologous molecule DR1, has revealed an overall shape typical of the class II histocompatibility molecules, yet with several novel features. These are unique to HLA-DQ and include: (1) an antigen-binding groove with a polymorphic first pocket and	en
heal.journalName	Journal of Structural Biology	en
dc.identifier.doi	10.1006/jsbi.1996.0079	en