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Ketoprofen versus paracetamol in the treatment of acute migraine

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dc.contributor.author Karabetsos, A en
dc.contributor.author Karachalios, G en
dc.contributor.author Bourlinou, P en
dc.contributor.author Reppa, A en
dc.contributor.author Koutri, R en
dc.contributor.author Fotiadou, A en
dc.date.accessioned 2014-03-01T01:45:57Z
dc.date.available 2014-03-01T01:45:57Z
dc.date.issued 1997 en
dc.identifier.issn 00178748 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/24814
dc.subject acute migraine en
dc.subject ketoprofen en
dc.subject paracetamol en
dc.subject.other ketoprofen en
dc.subject.other nonsteroid antiinflammatory agent en
dc.subject.other paracetamol en
dc.subject.other prostaglandin synthase inhibitor en
dc.subject.other adult en
dc.subject.other analgesia en
dc.subject.other article en
dc.subject.other clinical feature en
dc.subject.other clinical trial en
dc.subject.other controlled clinical trial en
dc.subject.other controlled study en
dc.subject.other crossover procedure en
dc.subject.other disease severity en
dc.subject.other double blind procedure en
dc.subject.other drug efficacy en
dc.subject.other drug safety en
dc.subject.other erythema en
dc.subject.other family history en
dc.subject.other female en
dc.subject.other human en
dc.subject.other intramuscular drug administration en
dc.subject.other major clinical study en
dc.subject.other male en
dc.subject.other migraine en
dc.subject.other pain assessment en
dc.subject.other priority journal en
dc.subject.other randomized controlled trial en
dc.subject.other tachycardia en
dc.subject.other Acetaminophen en
dc.subject.other Acute Disease en
dc.subject.other Adult en
dc.subject.other Analgesics, Non-Narcotic en
dc.subject.other Anti-Inflammatory Agents, Non-Steroidal en
dc.subject.other Double-Blind Method en
dc.subject.other Humans en
dc.subject.other Injections, Intramuscular en
dc.subject.other Ketoprofen en
dc.subject.other Migraine Disorders en
dc.title Ketoprofen versus paracetamol in the treatment of acute migraine en
heal.type journalArticle en
heal.identifier.primary 10.1046/j.1526-4610.1997.3701012.x en
heal.identifier.secondary http://dx.doi.org/10.1046/j.1526-4610.1997.3701012.x en
heal.publicationDate 1997 en
heal.abstract The efficacy and safety of ketoprofen and paracetamol were compared for the treatment of acute migraine in a randomized, double-blind study of 64 patients. Thirty-four patients received ketoprofen 100 mg intramuscularly, and 30 patients received paracetamol 500 mg intramuscularly. Partial or complete relief of pain and other symptoms was achieved 15 to 20 minutes after administration in the ketoprofen group and within 35 minutes in the paracetamol group. Complete relief of pain was achieved within 30 to 40 minutes after ketoprofen in 28 patients (82.5%) compared to 5 patients (17.5%) in the paracetamol group. Six of the patients treated with ketoprofen needed a second dose for complete relief of pain during the 4-hour follow-up period. Side effects were rare and minimal. Our findings suggest that ketoprofen produced statistically significant benefit in the treatment of acute migraine. en
heal.journalName Headache en
dc.identifier.doi 10.1046/j.1526-4610.1997.3701012.x en
dc.identifier.volume 37 en
dc.identifier.issue 1 en
dc.identifier.spage 12 en
dc.identifier.epage 14 en


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