Classic Kaposi's sarcoma in Greece: a clinico-epidemiological profile

Stratigos, JD; Potouridou, I; Katoulis, AC; Hatziolou, E; Christofidou, E; Stratigos, A; Hatzakis, A; Stavrianeas, NG

dc.contributor.author	Stratigos, JD	en
dc.contributor.author	Potouridou, I	en
dc.contributor.author	Katoulis, AC	en
dc.contributor.author	Hatziolou, E	en
dc.contributor.author	Christofidou, E	en
dc.contributor.author	Stratigos, A	en
dc.contributor.author	Hatzakis, A	en
dc.contributor.author	Stavrianeas, NG	en
dc.date.accessioned	2014-03-01T01:46:24Z
dc.date.available	2014-03-01T01:46:24Z
dc.date.issued	1997	en
dc.identifier.issn	0011-9059	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/24899
dc.subject.classification	Dermatology	en
dc.subject.other	DNA-SEQUENCES	en
dc.subject.other	MALIGNANCIES	en
dc.subject.other	ASSOCIATION	en
dc.subject.other	SARDINIA	en
dc.subject.other	ANTIGENS	en
dc.subject.other	HLA	en
dc.title	Classic Kaposi's sarcoma in Greece: a clinico-epidemiological profile	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	1997	en
heal.abstract	Background Classic Kaposi's sarcoma (CKS) is not uncommon in Greece with a reported incidence of 0.20 per 100,000 per year. Methods Epidemiological, clinical and histological features of all CKS cases, diagnosed in 'A. Sygros' hospital, Athens, Greece during the years 1989-1994, have been recorded and studied prospectively. Results During the five-year period studied, 66 CKS patients have been diagnosed in our hospital. Incidence among dermatologic patients was 2.11 per 10,000 patients examined, representing 1.35% of total skin malignancies. Patients' age at diagnosis ranged from 53 to 94 years (mean 72+/-8.8). The male to female ratio was 2.47:1. A high proportion of the patients were born in Peloponnesos (42.42%) and were residing in Athens (51.51%) or in Peloponnesos (24.24%). Nodules and/or plaques were the most frequent type of lesion, most commonly located on the feet (43.93%) or the hands (28.78%). Accompanying edema was seen in 51.51% of the patients. There were 16 stage I patients (24.24%), 40 stage II (60.60%), 0 stage III and 10 stage IV (15.15%). Involvement of visceral organs was detected in seven patients (10.60%), while 10 had lymph node involvement (15.15%) and three, involvement of the underlying bones (4.54%). Second primary malignancy was diagnosed in 6 cases (9.09%), most often of the reticuloendothelial system (83.33%). Conclusions CKS in Greece exhibits some special characteristics, including older age of onset; lower male to female ratio; endemic clustering; disseminated skin disease at diagnosis, often accompanied by lymphedema; not unusual visceral or lymph node involvement and association with second malignancies. We suggest that CKS in Greece possibly represents a distinct endemic subtype of CKS.	en
heal.publisher	BLACKWELL SCIENCE LTD	en
heal.journalName	INTERNATIONAL JOURNAL OF DERMATOLOGY	en
dc.identifier.isi	ISI:A1997YE85000004	en
dc.identifier.volume	36	en
dc.identifier.issue	10	en
dc.identifier.spage	735	en
dc.identifier.epage	740	en