Mixed cryoglobulinemia in Greece - Primary disorders in 10 cases

Boki, KA; Linardaki, GD; Galanopoulou, V; Vaiopoulos, G; Tzioufas, AG; Moutsopoulos, HM

dc.contributor.author	Boki, KA	en
dc.contributor.author	Linardaki, GD	en
dc.contributor.author	Galanopoulou, V	en
dc.contributor.author	Vaiopoulos, G	en
dc.contributor.author	Tzioufas, AG	en
dc.contributor.author	Moutsopoulos, HM	en
dc.date.accessioned	2014-03-01T01:46:31Z
dc.date.available	2014-03-01T01:46:31Z
dc.date.issued	1997	en
dc.identifier.issn	0300-9742	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/24924
dc.subject	mixed cryoglobulinemia	en
dc.subject	hepatitis virus	en
dc.subject	Sjogren's syndrome	en
dc.subject.classification	Rheumatology	en
dc.subject.other	HEPATITIS-C VIRUS	en
dc.subject.other	PRIMARY SJOGRENS-SYNDROME	en
dc.subject.other	HUMAN RHEUMATOID FACTORS	en
dc.subject.other	B VIRUS	en
dc.subject.other	INFECTION	en
dc.subject.other	ANTIBODIES	en
dc.subject.other	LYMPHOMA	en
dc.subject.other	COMMON	en
dc.title	Mixed cryoglobulinemia in Greece - Primary disorders in 10 cases	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	1997	en
heal.abstract	Mixed cryoglobulinemia (MC) is a systemic disorder whose pathogenesis is based on the presence of serum cryoglobulins. The purpose of this study was to evaluate on a prospective basis patients presenting with MC with regard to the clinical manifestations and the underlying disorders. We present ten patients with MC, who were diagnosed and followed up during a one year period in the Division of autoimmune rheumatic diseases (Clinical Department of Pathophysiology). MC was associated with hepatitis C virus (HCV) infection in two cases, with hepatitis B virus (HBV) infection in six, one patient had both HCV and evidence of HBV infection. while the remaining three patients fulfilled European classification criteria for diagnosis of Sjogren's sydrome (SS). In all ten cases, the presence of an underlying factor was identified, being either viral or autoimmune. It is concluded therefore that all patients presenting with MC should be completely evaluated for a hepatitis virus infection or an autoimmune or lymphoproliferative disorder. Furthermore, since the initiation of the process of MC is triggered by many factors, research should be directed towards the identification of the underlying common denominator.	en
heal.publisher	SCANDINAVIAN UNIVERSITY PRESS	en
heal.journalName	SCANDINAVIAN JOURNAL OF RHEUMATOLOGY	en
dc.identifier.isi	ISI:A1997XV33200008	en
dc.identifier.volume	26	en
dc.identifier.issue	4	en
dc.identifier.spage	280	en
dc.identifier.epage	286	en