Trace elements, age, and sex in amyotrophic lateral sclerosis disease

Kanias, GD; Kapaki, E

dc.contributor.author	Kanias, GD	en
dc.contributor.author	Kapaki, E	en
dc.date.accessioned	2014-03-01T01:46:37Z
dc.date.available	2014-03-01T01:46:37Z
dc.date.issued	1997	en
dc.identifier.issn	0163-4984	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/24951
dc.subject	trace elements	en
dc.subject	serum	en
dc.subject	cerebrospinal fluid	en
dc.subject	sex	en
dc.subject	age	en
dc.subject	amyotrophic lateral sclerosis	en
dc.subject.classification	Biochemistry & Molecular Biology	en
dc.subject.classification	Endocrinology & Metabolism	en
dc.title	Trace elements, age, and sex in amyotrophic lateral sclerosis disease	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	1997	en
heal.abstract	The statistical tests analysis of variance, analysis of-covariance, correlation coefficient, Kolmogorov-Smirnov test, t-test, and Tukey test were applied to copper, magnesium, manganese,and zinc content in serum (S) and in cerebrospinal fluid (CSF) of controls and of a sporadic form of Amyotrophic Lateral Sclerosis (ALS) disease. This is carried out in order to evaluate statistically the possible relationships among the trace elements when ALS patients and controls are considered as independent groups, within sex groups and within age decades of both patients and control classes. A statistically significant difference between older controls (age > 40) and ALS patients (age > 40) for copper in CSF, copper in S, manganese in S, and zinc in CSF was found. Statistically significant correlation coefficients within the different classes formed for this study were observed. Within this pool, a correlation of patient group can differ statistically from the corresponding one of controls and vice versa. Thus, this correlation could be characteristic of the group from which is extracted, e.g., the correlation between copper in S and zinc in S, which is characteristic of ALS patients when considered as an independent group as well as members of the male patient class.	en
heal.publisher	HUMANA PRESS INC	en
heal.journalName	BIOLOGICAL TRACE ELEMENT RESEARCH	en
dc.identifier.isi	ISI:A1997WZ27900005	en
dc.identifier.volume	56	en
dc.identifier.issue	2	en
dc.identifier.spage	187	en
dc.identifier.epage	201	en