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Laser excited autofluorescence for discrimination of atherosclerosis

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dc.contributor.author Makropoulou, M en
dc.contributor.author Drakaki, H en
dc.contributor.author Anastassopoulou, N en
dc.contributor.author Raptis, YS en
dc.contributor.author Serafetinides, AA en
dc.contributor.author Pafiti, A en
dc.contributor.author Tsiligiris, B en
dc.contributor.author Arapoglou, B en
dc.contributor.author Demakakos, P en
dc.date.accessioned 2014-03-01T01:48:36Z
dc.date.available 2014-03-01T01:48:36Z
dc.date.issued 1999 en
dc.identifier.issn 0277786X en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/25532
dc.relation.uri http://www.scopus.com/inward/record.url?eid=2-s2.0-0032659191&partnerID=40&md5=1f33fc7a5be2457c9c772e0814af8bc7 en
dc.subject.other Blood vessels en
dc.subject.other Calcification (biochemistry) en
dc.subject.other Chromophores en
dc.subject.other Diagnosis en
dc.subject.other Fluorescence en
dc.subject.other Laser applications en
dc.subject.other Lipids en
dc.subject.other Spectroscopic analysis en
dc.subject.other Tissue en
dc.subject.other Ultraviolet radiation en
dc.subject.other Laser excited autofluorescence en
dc.subject.other Noninvasive medical procedures en
dc.title Laser excited autofluorescence for discrimination of atherosclerosis en
heal.type journalArticle en
heal.publicationDate 1999 en
heal.abstract Experiments on atherosclerotic plaque diagnosis were carried out using laser induced fluorescence (LIF) spectroscopy on carotid plaque specimens. The excitation laser was a nitrogen laser, emitting pulses at a wavelength of 337 nm. Over 10 samples were examined in vitro and several spectra were obtained from each sample. Results were compared with conventional clinical techniques, such as histopathological diagnosis, which showed three areas of different composition on the pathological samples: fibrous tissue, lipid constituents and calcified plaque. An effort was made to distinguish the composition of the sample from the obtained spectra. Also, the results were compared with our previous work using longer excitation wavelengths. Spectral morphology of UV excited fluorescence reveals multi-peaks lineshapes, as a result of the superposition of different tissue chromophore signals. However, there was no observed specific wavelength where spectra corresponding to fibrous tissue, calcified tissue and lipid constituents have peaks. en
heal.publisher Society of Photo-Optical Instrumentation Engineers, Bellingham, WA, United States en
heal.journalName Proceedings of SPIE - The International Society for Optical Engineering en
dc.identifier.volume 3564 en
dc.identifier.spage 68 en
dc.identifier.epage 75 en


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