Familial cases of poikiloderma of Civatte: genetic implications in its pathogenesis?

Katoulis, AC; Stavrianeas, NG; Georgala, S; Katsarou-Katsari, A; Koumantaki-Mathioudaki, E; Antoniou, C; Stratigos, JD

dc.contributor.author	Katoulis, AC	en
dc.contributor.author	Stavrianeas, NG	en
dc.contributor.author	Georgala, S	en
dc.contributor.author	Katsarou-Katsari, A	en
dc.contributor.author	Koumantaki-Mathioudaki, E	en
dc.contributor.author	Antoniou, C	en
dc.contributor.author	Stratigos, JD	en
dc.date.accessioned	2014-03-01T01:48:53Z
dc.date.available	2014-03-01T01:48:53Z
dc.date.issued	1999	en
dc.identifier.issn	0307-6938	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/25626
dc.subject.classification	Dermatology	en
dc.title	Familial cases of poikiloderma of Civatte: genetic implications in its pathogenesis?	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	1999	en
heal.abstract	Poikiloderma of Civatte (PC) is a rather common, benign skin condition of obscure etiopathogenesis: cumulative exposure to UV radiation, hormonal changes associated with the menopause, and photo-allergic mechanisms have been implicated. We present seven cases of PC among the members of two unrelated Greek families, who have not shared common extrinsic influences, Literature review revealed no other reported familial cases. Familial tendencies, as well as the not unusual occurrence of PC in individuals with minimal sun exposure, and who are not using perfumes or cosmetics, provide support for the hypothesis that a genetic predisposition to the disease may exist; this predisposition is possibly transmitted as an autosomal dominant trait.	en
heal.publisher	BLACKWELL SCIENCE LTD	en
heal.journalName	CLINICAL AND EXPERIMENTAL DERMATOLOGY	en
dc.identifier.isi	ISI:000083319700012	en
dc.identifier.volume	24	en
dc.identifier.issue	5	en
dc.identifier.spage	385	en
dc.identifier.epage	387	en