Serum angiogenin levels in the female from birth to postmenopause

Malamitsi-Puchner, A; Tziotis, J; Tsonou, A; Sarandakou, A; Bartsocas, CS; Creatsas, G

dc.contributor.author	Malamitsi-Puchner, A	en
dc.contributor.author	Tziotis, J	en
dc.contributor.author	Tsonou, A	en
dc.contributor.author	Sarandakou, A	en
dc.contributor.author	Bartsocas, CS	en
dc.contributor.author	Creatsas, G	en
dc.date.accessioned	2014-03-01T01:49:03Z
dc.date.available	2014-03-01T01:49:03Z
dc.date.issued	1999	en
dc.identifier.issn	0897-7194	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/25653
dc.subject	angiogenin	en
dc.subject	female	en
dc.subject	neonate	en
dc.subject	menstrual cycle	en
dc.subject	pregnancy	en
dc.subject	postmenopause	en
dc.subject.classification	Cell Biology	en
dc.subject.classification	Endocrinology & Metabolism	en
dc.subject.other	SITE-DIRECTED MUTAGENESIS	en
dc.subject.other	MESSENGER-RNA	en
dc.subject.other	RIBONUCLEASE	en
dc.subject.other	EXPRESSION	en
dc.subject.other	INHIBITOR	en
dc.subject.other	CELLS	en
dc.subject.other	TUMOR	en
dc.subject.other	PROTEIN	en
dc.subject.other	INVITRO	en
dc.subject.other	ALPHA	en
dc.title	Serum angiogenin levels in the female from birth to postmenopause	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	1999	en
heal.abstract	This study investigated serum angiogenin levels of the potent angiogenic factor angiogenin, during fetal and neonatal Life, childhood, adulthood, pregnancy and postmenopause and compared them with respective levels in age-matched males, Serum angiogenin levels were measured by an enzyme immunoassay in 139 healthy male and female subjects, allocated in the above six groups, Multiple linear regression applied (a) for both genders and (b) only for females showed serum angiogenin levels in adults to differ statistically highly significantly from levels in cord blood (P = 0.0001), neonates (P = 0.0001), children (P = 0.0001), and pregnant women (P = 0.01), but not from "elderly" subjects (P = 0.80), A significant difference existed between levels in the proliferative and secretory phase of the menstrual cycle (P = 0.006), Furthermore, a significant trend for serum angiogenin levels,vith advancing age groups was noted (P = 0.0001), In conclusion, serum angiogenin levels increase significantly from fetal life to adulthood, possibly implying additional biological functions to that of angiogenesis.	en
heal.publisher	HARWOOD ACAD PUBL GMBH	en
heal.journalName	GROWTH FACTORS	en
dc.identifier.isi	ISI:000082497900007	en
dc.identifier.volume	17	en
dc.identifier.issue	1	en
dc.identifier.spage	75	en
dc.identifier.epage	79	en