New supramolecular complexes of manganese(II) and cobalt(II) with nucleic bases. Crystal structures of [M(H2O)(6)(1-Mecyt)(6)][ClO4](2)center dot H2O, [Co(1-Mecyt)(4)][ClO4](2) and [M(H2O)(4)(cyt)(2)][ClO4](2)center dot 2cyt center dot 2H(2)O [M = Co-II or Mn-II; cyt = cytosine; 1-Mecyt=1-methylcytosine]

De Munno, G; Medaglia, M; Armentano, D; Anastassopoulou, J; Theophanides, T

dc.contributor.author	De Munno, G	en
dc.contributor.author	Medaglia, M	en
dc.contributor.author	Armentano, D	en
dc.contributor.author	Anastassopoulou, J	en
dc.contributor.author	Theophanides, T	en
dc.date.accessioned	2014-03-01T01:50:04Z
dc.date.available	2014-03-01T01:50:04Z
dc.date.issued	2000	en
dc.identifier.issn	0300-9246	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/25987
dc.subject.classification	Chemistry, Inorganic & Nuclear	en
dc.subject.other	METAL-BINDING MODE	en
dc.subject.other	MOLECULAR RECOGNITION	en
dc.subject.other	1-METHYLCYTOSINE	en
dc.subject.other	NUCLEOBASES	en
dc.subject.other	CHEMISTRY	en
dc.subject.other	PERSPECTIVES	en
dc.subject.other	HEXAHYDRATE	en
dc.subject.other	COPPER(II)	en
dc.subject.other	DIHYDRATE	en
dc.subject.other	DINITRATE	en
dc.title	New supramolecular complexes of manganese(II) and cobalt(II) with nucleic bases. Crystal structures of [M(H2O)(6)(1-Mecyt)(6)][ClO4](2)center dot H2O, [Co(1-Mecyt)(4)][ClO4](2) and [M(H2O)(4)(cyt)(2)][ClO4](2)center dot 2cyt center dot 2H(2)O [M = Co-II or Mn-II; cyt = cytosine; 1-Mecyt=1-methylcytosine]	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	2000	en
heal.abstract	The reactivity of cytosine [cyt] and 1-methylcytosine [1-Mecyt] towards transition metal ions Mn2+ and Co2+ has been tested through the analysis of their complexes. Two new compounds have been obtained from 1-Mecyt in aqueous medium, [M(H2O)(6)(1-Mecyt)(6)][ClO4](2). H2O [M=Mn-II 1 or Co-II 2], and consist of hexaaqua ions linked to six 1-Mecyt molecules in such a way as to constitute a supramolecular cationic entity. Crystallization water molecules join the supramolecular assemblies by means of hydrogen bonds. Perchlorate anions, which are held in the crystal by electrostatic interactions with the cationic assemblies, insure the electroneutrality of the compounds. Compound 2 (pale pink crystals), when not filtered, over time disappears and gives rise to dark pink crystals of formula [Co(1-Mecyt)(4)][ClO4](2) 3. Compound 3 contains four 1-Mecyt molecules directly linked through N(3) atoms to Co2+ ions in a tetrahedral arrangement. No water molecule is present. The [Co(1-Mecyt)(4)](2+) cationic units are joined together through hydrogen bonds and form a chain. Perchlorate anions hold these cationic chains together by means of electrostatic forces. The reaction of cyt with Mn2+ and Co2+ ions leads to compounds of formulae [M(H2O)(4)(cyt)(2)][ClO4](2). 2cyt . 2H(2)O [M=Mn2+ 4 or Co2+ 5] in which base pairs are formed between the two unco-ordinated cytosine molecules and those co-ordinated to the metal ion through the O(2) atom. Each metal ion is six-co-ordinated, being linked also to four water molecules. Perchlorate anions and crystallization water molecules interact with the base pairs and the metal ion through hydrogen bonds to form five-membered rings. The cobalt(II) compound constitutes the first example of cytosine-cobalt(II) co-ordination via O(2).	en
heal.publisher	ROYAL SOC CHEMISTRY	en
heal.journalName	JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS	en
dc.identifier.isi	ISI:000087323100017	en
dc.identifier.volume	10	en
dc.identifier.spage	1625	en
dc.identifier.epage	1629	en