Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage

Alexopoulos, L; Williams, G; Upton, M; Setton, L; Guilak, F

dc.contributor.author	Alexopoulos, L	en
dc.contributor.author	Williams, G	en
dc.contributor.author	Upton, M	en
dc.contributor.author	Setton, L	en
dc.contributor.author	Guilak, F	en
dc.date.accessioned	2014-03-01T01:54:19Z
dc.date.available	2014-03-01T01:54:19Z
dc.date.issued	2005	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/27313
dc.subject	Articular Cartilage	en
dc.subject	Cell Mechanics	en
dc.subject	Degeneration	en
dc.subject	Extracellular Matrix	en
dc.subject	Finite Element Model	en
dc.subject	Fluid Flow	en
dc.subject	Mechanical Property	en
dc.subject	Osteoarthritis	en
dc.subject	poisson's ratio	en
dc.subject	Theoretical Model	en
dc.subject	young's modulus	en
dc.title	Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/j.jbiomech.2004.04.012	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.jbiomech.2004.04.012	en
heal.publicationDate	2005	en
heal.abstract	The pericellular matrix (PCM) is a narrow region of cartilaginous tissue that surrounds chondrocytes in articular cartilage. Previous modeling studies indicate that the mechanical properties of the PCM relative to those of the extracellular matrix (ECM) can significantly affect the stress–strain, fluid flow, and physicochemical environments of the chondrocyte, suggesting that the PCM plays a biomechanical role in articular cartilage.	en
heal.journalName	Journal of Biomechanics	en
dc.identifier.doi	10.1016/j.jbiomech.2004.04.012	en