The effect of transcranial magnetic stimulation on the latencies of vertical saccades

Tzelepi, A; Yang, Q; Kapoula, Z

dc.contributor.author	Tzelepi, A	en
dc.contributor.author	Yang, Q	en
dc.contributor.author	Kapoula, Z	en
dc.date.accessioned	2014-03-01T01:54:30Z
dc.date.available	2014-03-01T01:54:30Z
dc.date.issued	2005	en
dc.identifier.issn	00144819	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/27423
dc.subject	Delay task	en
dc.subject	Fixation disengagement	en
dc.subject	Gap task	en
dc.subject	Posterior parietal cortex	en
dc.subject	Spatial attention	en
dc.subject	Vertical asymmetry	en
dc.subject.other	adult	en
dc.subject.other	article	en
dc.subject.other	controlled study	en
dc.subject.other	eye fixation	en
dc.subject.other	eye movement	en
dc.subject.other	eye movement control	en
dc.subject.other	female	en
dc.subject.other	human	en
dc.subject.other	human experiment	en
dc.subject.other	latent period	en
dc.subject.other	male	en
dc.subject.other	normal human	en
dc.subject.other	parietal lobe	en
dc.subject.other	priority journal	en
dc.subject.other	saccadic eye movement	en
dc.subject.other	task performance	en
dc.subject.other	time	en
dc.subject.other	transcranial magnetic stimulation	en
dc.subject.other	vision	en
dc.subject.other	Adult	en
dc.subject.other	Attention	en
dc.subject.other	Electric Stimulation	en
dc.subject.other	Female	en
dc.subject.other	Fixation, Ocular	en
dc.subject.other	Humans	en
dc.subject.other	Male	en
dc.subject.other	Middle Aged	en
dc.subject.other	Muscle Contraction	en
dc.subject.other	Oculomotor Muscles	en
dc.subject.other	Orientation	en
dc.subject.other	Parietal Lobe	en
dc.subject.other	Psychomotor Performance	en
dc.subject.other	Reaction Time	en
dc.subject.other	Saccades	en
dc.subject.other	Transcranial Magnetic Stimulation	en
dc.title	The effect of transcranial magnetic stimulation on the latencies of vertical saccades	en
heal.type	journalArticle	en
heal.identifier.primary	10.1007/s00221-005-2250-9	en
heal.identifier.secondary	http://dx.doi.org/10.1007/s00221-005-2250-9	en
heal.publicationDate	2005	en
heal.abstract	In this study, we investigated the effect of transcranial magnetic stimulation (TMS) over the right posterior parietal cortex (PPC) on the latency of two different types of visually-guided vertical saccades: reflexive saccades triggered by the sudden onset of a target, and saccades towards target locations known in advance. For this reason, we used two oculomotor tasks: a gap and a delay task, respectively. Nine normal subjects performed vertical saccades at ±7.5 and ±15°. TMS was applied at 80 and 100 ms after target onset in the gap task, and after fixation offset in the delay task. Without TMS, we confirmed a latency asymmetry in the gap task favouring upward saccades at the lower eccentricity (7.5°), and a latency symmetry in the delay task. TMS increased the latencies of all saccades in the delay task, when delivered at 100 ms. This effect was mostly pronounced for downward saccades at 7.5°. As a result, saccade latencies showed an asymmetry in this condition, similar to the one observed in the gap task without TMS. The gap task with TMS resulted in a variable latency distribution and no significant overall effect on saccade latency. Our results indicate that the right PPC is involved in the initiation of vertical saccades in the delay task, and that this involvement appears to be enhanced for downward saccades. A conclusion for the involvement of this area in the gap task could not be drawn from this study. © Springer-Verlag 2005.	en
heal.journalName	Experimental Brain Research	en
dc.identifier.doi	10.1007/s00221-005-2250-9	en
dc.identifier.volume	164	en
dc.identifier.issue	1	en
dc.identifier.spage	67	en
dc.identifier.epage	77	en