Crystal structure, spectroscopic, and biological study of the copper(II) complex with third-generation quinolone antibiotic sparfloxacin

Efthimiadou, EK; Sanakis, Y; Raptopoulou, CP; Karaliota, A; Katsaros, N; Psomas, G

dc.contributor.author	Efthimiadou, EK	en
dc.contributor.author	Sanakis, Y	en
dc.contributor.author	Raptopoulou, CP	en
dc.contributor.author	Karaliota, A	en
dc.contributor.author	Katsaros, N	en
dc.contributor.author	Psomas, G	en
dc.date.accessioned	2014-03-01T01:55:31Z
dc.date.available	2014-03-01T01:55:31Z
dc.date.issued	2006	en
dc.identifier.issn	0960-894X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/27774
dc.subject	quinolones	en
dc.subject	Sparfloxacin	en
dc.subject	Cu(II) complex	en
dc.subject	EPR spectroscopy	en
dc.subject	interaction with calf-thymus DNA	en
dc.subject	MIC	en
dc.subject.classification	Chemistry, Medicinal	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	MIXED-LIGAND COMPLEXES	en
dc.subject.other	N-N DONORS	en
dc.subject.other	METAL-IONS	en
dc.subject.other	CIPROFLOXACIN	en
dc.subject.other	FAMILY	en
dc.subject.other	DNA	en
dc.subject.other	ANTIBACTERIAL	en
dc.subject.other	NORFLOXACIN	en
dc.subject.other	CU(II)	en
dc.subject.other	NI(II)	en
dc.title	Crystal structure, spectroscopic, and biological study of the copper(II) complex with third-generation quinolone antibiotic sparfloxacin	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	2006	en
heal.abstract	The neutral mononuclear copper(II) complex with the quinolone antibacterial drug sparfloxacin has been prepared and characterized with 1R, UV-vis, and EPR spectroscopies and X-ray crystallography. The interaction of the complex with calf-thymus DNA has also been investigated and the antimicrobial activity has been evaluated against three different microorganisms. (c) 2006 Elsevier Ltd. All rights reserved.	en
heal.publisher	PERGAMON-ELSEVIER SCIENCE LTD	en
heal.journalName	BIOORGANIC & MEDICINAL CHEMISTRY LETTERS	en
dc.identifier.isi	ISI:000238698400050	en
dc.identifier.volume	16	en
dc.identifier.issue	14	en
dc.identifier.spage	3864	en
dc.identifier.epage	3867	en