Chios mastic gum modulates serum biochemical parameters in a human population

Triantafyllou, A; Chaviaras, N; Sergentanis, TN; Protopapa, E; Tsaknis, J

dc.contributor.author	Triantafyllou, A	en
dc.contributor.author	Chaviaras, N	en
dc.contributor.author	Sergentanis, TN	en
dc.contributor.author	Protopapa, E	en
dc.contributor.author	Tsaknis, J	en
dc.date.accessioned	2014-03-01T01:56:28Z
dc.date.available	2014-03-01T01:56:28Z
dc.date.issued	2007	en
dc.identifier.issn	0378-8741	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/28108
dc.subject	Pistacia lentiscus	en
dc.subject	Chios mastic	en
dc.subject	cholesterol	en
dc.subject	lipoprotein	en
dc.subject	apolipoprotein	en
dc.subject	aminotransferase	en
dc.subject.classification	Plant Sciences	en
dc.subject.classification	Chemistry, Medicinal	en
dc.subject.classification	Integrative & Complementary Medicine	en
dc.subject.classification	Pharmacology & Pharmacy	en
dc.subject.other	LENTISCUS VAR. CHIA	en
dc.subject.other	CATALYTIC ACTIVITY CONCENTRATIONS	en
dc.subject.other	CORONARY-ARTERY-DISEASE	en
dc.subject.other	PISTACIA-LENTISCUS	en
dc.subject.other	HELICOBACTER-PYLORI	en
dc.subject.other	ANTIMICROBIAL ACTIVITY	en
dc.subject.other	IN-VITRO	en
dc.subject.other	CHEMICAL-COMPOSITION	en
dc.subject.other	HEART-DISEASE	en
dc.subject.other	CHEWING GUM	en
dc.title	Chios mastic gum modulates serum biochemical parameters in a human population	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	2007	en
heal.abstract	Introduction: Current research suggests that Chios mastic (Pistacia lentiscus var. chia) possesses beneficial (antimicrobial, antioxidant, hepatoprotective) properties. This study aims to assess its effects on cardiologic and hepatic biochemical indices of human subjects. Materials and methods: Subjects (n = 133, aged over 50) were randomly assigned to two groups, the first (high-dose group) ingesting daily 5 g of mastic powder and the second receiving daily a Chios mastic solution (low-dose group). Serum biochemical parameters were determined on a monthly basis for an 18-month (high-dose group) and a 12-month (low-dose group) follow-up period. Generalized least squares random-effects linear regression was performed. Results: The group ingesting Chios mastic powder (high-dose group) exhibited a decrease in serum total cholesterol, LDL, total cholesterol/HDL ratio, lipoprotein (a), apolipoprotein A-1, apolipoprotein B (apoB/apoA-1 ratio did not change), SGOT, SGPT and gamma-GT levels; in the second (low-dose) group, glucose levels decreased in males. Discussion: Chios mastic powder could have a hepatoprotective/cardioprotective role in vivo in humans. (c) 2006 Elsevier Ireland Ltd. All rights reserved.	en
heal.publisher	ELSEVIER IRELAND LTD	en
heal.journalName	JOURNAL OF ETHNOPHARMACOLOGY	en
dc.identifier.isi	ISI:000246059600008	en
dc.identifier.volume	111	en
dc.identifier.issue	1	en
dc.identifier.spage	43	en
dc.identifier.epage	49	en