Changes of liver and muscle enzymes activity in patients with rigor

Sevastos, N; Manesis, EK; Savvas, SP; Galiatsatos, N; Papatheodoridis, GV; Archimandritis, AJ

dc.contributor.author	Sevastos, N	en
dc.contributor.author	Manesis, EK	en
dc.contributor.author	Savvas, SP	en
dc.contributor.author	Galiatsatos, N	en
dc.contributor.author	Papatheodoridis, GV	en
dc.contributor.author	Archimandritis, AJ	en
dc.date.accessioned	2014-03-01T01:57:19Z
dc.date.available	2014-03-01T01:57:19Z
dc.date.issued	2008	en
dc.identifier.issn	0953-6205	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/28400
dc.subject	rigor	en
dc.subject	liver enzymes	en
dc.subject	creatinophosphokinase	en
dc.subject	lactate dehydrogenase	en
dc.subject	bacteremia	en
dc.subject	infection	en
dc.subject.classification	Medicine, General & Internal	en
dc.subject.other	EXTRAHEPATIC INFECTION	en
dc.subject.other	BACTERIAL INFECTIONS	en
dc.subject.other	JAUNDICE	en
dc.subject.other	BACTEREMIA	en
dc.subject.other	FREQUENCY	en
dc.subject.other	ENDOTOXIN	en
dc.title	Changes of liver and muscle enzymes activity in patients with rigor	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	2008	en
heal.abstract	Aim: We investigated whether changes of liver and muscle enzymes activity are associated with rigor of several causes and have any prognostic significance. Methods: Seventy-five patients with rigor were prospectively evaluated. Serum enzymes were measured at the onset of rigor and during the three following days. Results: Causes of rigor were bacteremia (n=28), cholangiitis (n=12), protozoan infections (n=9), viral infections (n=10) and platelet transfusions (n=16). Increases in enzymes activity were observed with rigors from infectious causes, but not with that following platelet transfusions. Patients with cholangiitis demonstrated the highest ALT elevations, while those with viral infections the highest CPK levels. In bacteremia, CPK values increased significantly only in cases with dehydration and hypokalemia. Conclusions: Rigor per se does not cause increases in muscle or liver enzymes activities. Rather these changes are associated with the rigor's causative agent (infectious or not), the patient's general condition and the severity and extent of the underlying disease. (c) 2007 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.	en
heal.publisher	ELSEVIER SCIENCE BV	en
heal.journalName	EUROPEAN JOURNAL OF INTERNAL MEDICINE	en
dc.identifier.isi	ISI:000253941600006	en
dc.identifier.volume	19	en
dc.identifier.issue	2	en
dc.identifier.spage	109	en
dc.identifier.epage	114	en