Influence of sleep disturbance on quality of life of patients with epilepsy

Piperidou, C; Karlovasitou, A; Triantafyllou, N; Terzoudi, A; Constantinidis, T; Vadikolias, K; Heliopoulos, I; Vassilopoulos, D; Balogiannis, S

dc.contributor.author	Piperidou, C	en
dc.contributor.author	Karlovasitou, A	en
dc.contributor.author	Triantafyllou, N	en
dc.contributor.author	Terzoudi, A	en
dc.contributor.author	Constantinidis, T	en
dc.contributor.author	Vadikolias, K	en
dc.contributor.author	Heliopoulos, I	en
dc.contributor.author	Vassilopoulos, D	en
dc.contributor.author	Balogiannis, S	en
dc.date.accessioned	2014-03-01T01:57:26Z
dc.date.available	2014-03-01T01:57:26Z
dc.date.issued	2008	en
dc.identifier.issn	1059-1311	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/28417
dc.subject	Epilepsy	en
dc.subject	Excessive daytime sleepiness	en
dc.subject	Obstructive sleep apnea	en
dc.subject	Insomnia	en
dc.subject	Quality of life	en
dc.subject.classification	Clinical Neurology	en
dc.subject.classification	Neurosciences	en
dc.subject.other	EXCESSIVE DAYTIME SLEEPINESS	en
dc.subject.other	ANTIEPILEPTIC DRUGS	en
dc.subject.other	REFRACTORY EPILEPSY	en
dc.subject.other	SEIZURE FREQUENCY	en
dc.subject.other	APNEA SYNDROME	en
dc.subject.other	LOBE EPILEPSY	en
dc.subject.other	DISORDERS	en
dc.subject.other	SCALE	en
dc.subject.other	POPULATION	en
dc.subject.other	DEPRESSION	en
dc.title	Influence of sleep disturbance on quality of life of patients with epilepsy	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	2008	en
heal.abstract	The frequency of sleep disturbances in patients with epilepsy and their impact on quality of life (QoL) have been documented in a few reports, and the results are conflicting. We identified 124 consecutive epilepsy out-patients who visited the epilepsy out-patient clinics at the University Hospital of Alexandroupolis, the AHEPA Hospital in Thessaloniki and the Aeginitio Hospital in Athens. We measured excessive daytime sleepiness (EDS) with the Epworth Sleepiness Scale (ESS), obstructive sleep apnea (OSA) with the Sleep Apnea scale of the Sleep Disorders Questionnaire (SASDQ), and insomnia with the Athens Insomnia Scale (AIS). We evaluated quality of life by the Quality of Life in Epilepsy Inventory (QOLIE-31). EDS was found in 16.9% (21/124) of epileptic patients, OSA in 28.2% (35/124), and insomnia in 24.6% (30/122). In multivariate analysis, we found that insomnia was an independent negative factor for Total score (p < 0.001), Overall QoL (p = 0.002), Emotional well-being (p < 0.001), Energy/fatigue (p < 0.001), Cognitive functioning (p = 0.04) and Social functioning (p = 0.03), and OSA only for Cognitive functioning (p = 0.01). According to our findings, EDS, OSA, and insomnia are frequent in epileptic patients. Epileptic patients with sleep disturbance, mainly insomnia, have significant QoL impairment. (C) 2008 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.	en
heal.publisher	W B SAUNDERS CO LTD	en
heal.journalName	SEIZURE-EUROPEAN JOURNAL OF EPILEPSY	en
dc.identifier.isi	ISI:000260125000002	en
dc.identifier.volume	17	en
dc.identifier.issue	7	en
dc.identifier.spage	588	en
dc.identifier.epage	594	en