Structure, antimicrobial activity and DNA-binding properties of the cobalt(II)-sparfloxacin complex

Efthimiadou, EK; Karaliota, A; Psomas, G

dc.contributor.author	Efthimiadou, EK	en
dc.contributor.author	Karaliota, A	en
dc.contributor.author	Psomas, G	en
dc.date.accessioned	2014-03-01T01:57:36Z
dc.date.available	2014-03-01T01:57:36Z
dc.date.issued	2008	en
dc.identifier.issn	0960-894X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/28451
dc.subject	sparfloxacin	en
dc.subject	quinolones	en
dc.subject	cobalt(II) complex	en
dc.subject	interaction with calf-thymus DNA	en
dc.subject.classification	Chemistry, Medicinal	en
dc.subject.classification	Chemistry, Organic	en
dc.subject.other	MONONUCLEAR METAL-COMPLEXES	en
dc.subject.other	CALF THYMUS DNA	en
dc.subject.other	ANTIBACTERIAL ACTIVITY	en
dc.subject.other	CRYSTAL-STRUCTURES	en
dc.subject.other	CLEAVAGE ACTIVITY	en
dc.subject.other	NUCLEIC-ACIDS	en
dc.subject.other	SPARFLOXACIN	en
dc.subject.other	AGENTS	en
dc.subject.other	CIPROFLOXACIN	en
dc.subject.other	ENROFLOXACIN	en
dc.title	Structure, antimicrobial activity and DNA-binding properties of the cobalt(II)-sparfloxacin complex	en
heal.type	journalArticle	en
heal.language	English	en
heal.publicationDate	2008	en
heal.abstract	The neutral mononuclear cobalt(II) complex with sparfloxacin has been prepared and characterized with physicochemical, spectroscopic and electrochemical techniques and molecular mechanics calculations. The interaction of the complex with calf-thymus DNA has been investigated with UV spectroscopy, cyclic voltammetry and competitive studies with ethidium bromide. The antimicrobial activity of the complex has been tested against three microorganisms. (c) 2008 Elsevier Ltd. All rights reserved.	en
heal.publisher	PERGAMON-ELSEVIER SCIENCE LTD	en
heal.journalName	BIOORGANIC & MEDICINAL CHEMISTRY LETTERS	en
dc.identifier.isi	ISI:000257640400046	en
dc.identifier.volume	18	en
dc.identifier.issue	14	en
dc.identifier.spage	4033	en
dc.identifier.epage	4037	en