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Aldosterone receptor blockade inhibits degenerative processes in the early stage of calcific aortic stenosis

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dc.contributor.author Gkizas, S en
dc.contributor.author Koumoundourou, D en
dc.contributor.author Sirinian, X en
dc.contributor.author Rokidi, S en
dc.contributor.author Mavrilas, D en
dc.contributor.author Koutsoukos, P en
dc.contributor.author Papalois, A en
dc.contributor.author Apostolakis, E en
dc.contributor.author Alexopoulos, D en
dc.contributor.author Papadaki, H en
dc.date.accessioned 2014-03-01T01:59:07Z
dc.date.available 2014-03-01T01:59:07Z
dc.date.issued 2010 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/28838
dc.subject Angiotensin Converting Enzyme en
dc.subject Aortic Stenosis en
dc.subject Aortic Valve en
dc.subject Aortic Valve Disease en
dc.subject Blood Pressure en
dc.subject Immunohistochemistry en
dc.subject Potassium en
dc.subject Scanning Electron Microscopy en
dc.subject group 1 en
dc.subject High Fat Diet en
dc.subject Mineralocorticoid Receptor en
dc.subject New Zealand en
dc.title Aldosterone receptor blockade inhibits degenerative processes in the early stage of calcific aortic stenosis en
heal.type journalArticle en
heal.identifier.primary 10.1016/j.ejphar.2010.05.048 en
heal.identifier.secondary http://dx.doi.org/10.1016/j.ejphar.2010.05.048 en
heal.publicationDate 2010 en
heal.abstract Calcific aortic valve disease is associated with increased morbidity and mortality, especially in the elderly. To date, pharmacological therapies have not proven as effective as surgical intervention. Here, we used a hyperlipidemic rabbit model to investigate the potential effects of selective aldosterone inhibition on the early stages of aortic valve calcification, a pharmacological strategy that has not yet been tested. en
heal.journalName European Journal of Pharmacology en
dc.identifier.doi 10.1016/j.ejphar.2010.05.048 en


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