Immunohistochemical detection of phosphorylated JAK-2 and STAT5 proteins and correlation with erythropoietin receptor (EpoR) expression status in human brain tumors

Kondyli, M; Gatzounis, G; Kyritsis, A; Varakis, J; Assimakopoulou, M

dc.contributor.author	Kondyli, M	en
dc.contributor.author	Gatzounis, G	en
dc.contributor.author	Kyritsis, A	en
dc.contributor.author	Varakis, J	en
dc.contributor.author	Assimakopoulou, M	en
dc.date.accessioned	2014-03-01T01:59:18Z
dc.date.available	2014-03-01T01:59:18Z
dc.date.issued	2010	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/28909
dc.subject	Brain Development	en
dc.subject	Brain Tissue	en
dc.subject	Erythropoietin	en
dc.subject	Expression Profile	en
dc.subject	Glial Cell	en
dc.subject	Human Brain	en
dc.subject	Immunohistochemistry	en
dc.subject	Molecular Mechanics	en
dc.subject	Transcription Factor	en
dc.subject	constitutively active	en
dc.subject	Formalin Fixed Paraffin Embedded	en
dc.title	Immunohistochemical detection of phosphorylated JAK-2 and STAT5 proteins and correlation with erythropoietin receptor (EpoR) expression status in human brain tumors	en
heal.type	journalArticle	en
heal.identifier.primary	10.1007/s11060-010-0156-2	en
heal.identifier.secondary	http://dx.doi.org/10.1007/s11060-010-0156-2	en
heal.publicationDate	2010	en
heal.abstract	Phosphorylated (activated) forms of Janus Kinase 2 (pJAK-2) and STAT-5 transcription factor (pSTAT-5), which are preferentially expressed after binding of erythropoietin (Epo) to its receptor EpoR, are known to be implicated in the molecular mechanisms controlling brain development. The purpose of this study was to investigate the expression of these proteins (pJAK-2, pSTAT-5, and EpoR) in human brain tumors compared	en
heal.journalName	Journal of Neuro-oncology	en
dc.identifier.doi	10.1007/s11060-010-0156-2	en