A correlative study of quantitative EMG and biopsy findings in 31 patients with myopathies

Dardiotis, E; Papathanasiou, E; Vonta, I; Hadjigeorgiou, G; Zamba-Papanicolaou, E; Kyriakides, T

dc.contributor.author	Dardiotis, E	en
dc.contributor.author	Papathanasiou, E	en
dc.contributor.author	Vonta, I	en
dc.contributor.author	Hadjigeorgiou, G	en
dc.contributor.author	Zamba-Papanicolaou, E	en
dc.contributor.author	Kyriakides, T	en
dc.date.accessioned	2014-03-01T02:01:38Z
dc.date.available	2014-03-01T02:01:38Z
dc.date.issued	2011	en
dc.identifier.issn	11282460	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/29218
dc.relation.uri	http://www.scopus.com/inward/record.url?eid=2-s2.0-79958029482&partnerID=40&md5=8861003e25c4bb437450ae7649a4acaf	en
dc.subject	Muscle biopsy	en
dc.subject	Quantitative electromyography	en
dc.subject	Sensitivity	en
dc.subject.other	article	en
dc.subject.other	clinical article	en
dc.subject.other	electromyography	en
dc.subject.other	histopathology	en
dc.subject.other	human	en
dc.subject.other	human tissue	en
dc.subject.other	muscle biopsy	en
dc.subject.other	myopathy	en
dc.subject.other	neuromuscular system	en
dc.subject.other	Electromyography	en
dc.subject.other	Humans	en
dc.subject.other	Muscle, Skeletal	en
dc.subject.other	Muscular Diseases	en
dc.subject.other	Predictive Value of Tests	en
dc.subject.other	Sensitivity and Specificity	en
dc.title	A correlative study of quantitative EMG and biopsy findings in 31 patients with myopathies	en
heal.type	journalArticle	en
heal.publicationDate	2011	en
heal.abstract	A direct correlation of QEMG with muscle biopsy findings might help delineate the sensitivity of QEMG in identifying muscle pathology as well as provide information on electrophysiological-histological correlations. In a study of 31 patients with a variety of myopathies we found that the sensitivity of QEMG was between 24 to 69% depending of the specific method of signal analysis. The positive predictive value of abnormal QEMG was more than 90% while its negative predictive value was only about 20%. Amplitude outlier analysis was superior especially in minimally weak muscles (MRC > 4) and was particularly sensitive at detecting increased variability in fiber size and more subtle myopathic changes.	en
heal.journalName	Acta Myologica	en
dc.identifier.volume	30	en
dc.identifier.issue	JUNE	en
dc.identifier.spage	37	en
dc.identifier.epage	41	en