Magnetically targeted drug delivery during cardiopulmonary resuscitation and the post-resuscitation period

Xanthos, T; Chatzigeorgiou, M; Johnson, EO; Chalkias, A

dc.contributor.author	Xanthos, T	en
dc.contributor.author	Chatzigeorgiou, M	en
dc.contributor.author	Johnson, EO	en
dc.contributor.author	Chalkias, A	en
dc.date.accessioned	2014-03-01T02:09:30Z
dc.date.available	2014-03-01T02:09:30Z
dc.date.issued	2012	en
dc.identifier.issn	03009572	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/29857
dc.subject	Cardiopulmonary resuscitation	en
dc.subject	Magnetically targeted drug delivery	en
dc.subject	Post-cardiac arrest period	en
dc.subject	Treatment	en
dc.subject.other	magnetic nanoparticle	en
dc.subject.other	article	en
dc.subject.other	brain injury	en
dc.subject.other	drug delivery system	en
dc.subject.other	heart arrest	en
dc.subject.other	human	en
dc.subject.other	magnetism	en
dc.subject.other	nanotechnology	en
dc.subject.other	outcome assessment	en
dc.subject.other	priority journal	en
dc.subject.other	resuscitation	en
dc.title	Magnetically targeted drug delivery during cardiopulmonary resuscitation and the post-resuscitation period	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/j.resuscitation.2012.01.017	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.resuscitation.2012.01.017	en
heal.publicationDate	2012	en
heal.abstract	Treatment with pharmacological agents is frequently required during cardiopulmonary resuscitation efforts and almost always during the post-resuscitation period. However, the lack of scientific evidence, the potent side effects and the association of resuscitation drugs with poor outcome act as a disincentive for their use. The use of magnetic nanoparticles in medicine has great potential. Magnetically targeted drug delivery may be an ideal method of pharmaceutical treatment during the resuscitation efforts and post-resuscitation period. In addition, there is evidence that magnetic nanotechnology may be used in the detection of post-cardiac arrest brain injury. In the light of poor survival of cardiac arrest victims, research in cardiopulmonary resuscitation should focus on this promising technology as soon as possible. © 2012 Elsevier Ireland Ltd.	en
heal.journalName	Resuscitation	en
dc.identifier.doi	10.1016/j.resuscitation.2012.01.017	en
dc.identifier.volume	83	en
dc.identifier.issue	7	en
dc.identifier.spage	803	en
dc.identifier.epage	805	en