Single-trial magnetoencephalography signals encoded as an unfolding decision process

Smyrnis, N; Mylonas, DS; Rezaie, R; Siettos, CI; Ventouras, E; Ktonas, PY; Evdokimidis, I; Papanicolaou, AC

dc.contributor.author	Smyrnis, N	en
dc.contributor.author	Mylonas, DS	en
dc.contributor.author	Rezaie, R	en
dc.contributor.author	Siettos, CI	en
dc.contributor.author	Ventouras, E	en
dc.contributor.author	Ktonas, PY	en
dc.contributor.author	Evdokimidis, I	en
dc.contributor.author	Papanicolaou, AC	en
dc.date.accessioned	2014-03-01T02:14:37Z
dc.date.available	2014-03-01T02:14:37Z
dc.date.issued	2012	en
dc.identifier.issn	10538119	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/30073
dc.subject	ICA	en
dc.subject	Premotor potential	en
dc.subject	Reaction time	en
dc.subject	Visual evoked potential	en
dc.subject	Visuomotor	en
dc.subject	Voluntary movement	en
dc.subject.other	adult	en
dc.subject.other	article	en
dc.subject.other	brain region	en
dc.subject.other	cognition	en
dc.subject.other	controlled study	en
dc.subject.other	decision making	en
dc.subject.other	female	en
dc.subject.other	human	en
dc.subject.other	human experiment	en
dc.subject.other	magnetoencephalography	en
dc.subject.other	male	en
dc.subject.other	motor cortex	en
dc.subject.other	motor performance	en
dc.subject.other	nerve cell	en
dc.subject.other	normal human	en
dc.subject.other	prediction	en
dc.subject.other	premotor cortex	en
dc.subject.other	priority journal	en
dc.subject.other	response time	en
dc.subject.other	sensorimotor function	en
dc.subject.other	signal processing	en
dc.subject.other	stochastic model	en
dc.subject.other	volunteer	en
dc.subject.other	Adult	en
dc.subject.other	Decision Making	en
dc.subject.other	Female	en
dc.subject.other	Humans	en
dc.subject.other	Magnetoencephalography	en
dc.subject.other	Male	en
dc.subject.other	Reaction Time	en
dc.subject.other	Young Adult	en
dc.title	Single-trial magnetoencephalography signals encoded as an unfolding decision process	en
heal.type	journalArticle	en
heal.identifier.primary	10.1016/j.neuroimage.2011.10.091	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.neuroimage.2011.10.091	en
heal.publicationDate	2012	en
heal.abstract	The model of a stochastic decision process unfolding in motor and premotor regions of the brain was encoded in single-trial magnetoencephalographic (MEG) recordings while ten healthy subjects performed a sensorimotor Reaction Time (RT) task. The duration of single-trial MEG signals preceding the motor response, recorded over the motor cortex contralateral to the responding hand, co-varied with RT across trials according to the model's prediction. Furthermore, these signals displayed the same properties of a ""rising-to-a-fixed-threshold"" decision process as posited by the model and observed in the activity of single neurons in the primate cortex. The present findings demonstrate that non-averaged, single-trial MEG recordings can be used to test models of cognitive processes, like decision-making, in humans. © 2011 Elsevier Inc.	en
heal.journalName	NeuroImage	en
dc.identifier.doi	10.1016/j.neuroimage.2011.10.091	en
dc.identifier.volume	59	en
dc.identifier.issue	4	en
dc.identifier.spage	3604	en
dc.identifier.epage	3610	en