Dielectric changes precede hydrogen bond breakage during helix to coil transition of deoxyribonucleic acid

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dc.contributor.author Georgakilas Alexandros, G en
dc.contributor.author Haveles Kostas, S en
dc.contributor.author Konsta, Amalia en
dc.contributor.author Sideris Eleftherios, G en
dc.date.accessioned 2014-03-01T02:41:11Z
dc.date.available 2014-03-01T02:41:11Z
dc.date.issued 1996 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/30413
dc.subject deoxyribonucleic acid en
dc.subject Hydrogen Bond en
dc.subject Ionizing Radiation en
dc.subject Thermodynamic Stability en
dc.subject Low Dose en
dc.subject Molecular Weight en
dc.subject.other Biology en
dc.subject.other DNA en
dc.subject.other Gamma rays en
dc.subject.other Hydrogen bonds en
dc.subject.other Molecular weight en
dc.subject.other Molecules en
dc.subject.other Phase transitions en
dc.subject.other Radiation en
dc.subject.other Thermodynamic stability en
dc.subject.other Alpha irradiation en
dc.subject.other Helix to coil transition en
dc.subject.other Radiation biology en
dc.subject.other Thermal transition en
dc.subject.other Dielectric properties en
dc.title Dielectric changes precede hydrogen bond breakage during helix to coil transition of deoxyribonucleic acid en
heal.type conferenceItem en
heal.identifier.primary 10.1109/ISE.1996.578201 en
heal.identifier.secondary http://dx.doi.org/10.1109/ISE.1996.578201 en
heal.publicationDate 1996 en
heal.abstract An interesting and simultaneously unexpected thermodynamic stability of the DNA helix was observed when studying the effects of exposure to γ- and α-irradiation on the double helix to coil thermal transition phase of mammalian macromolecular DNA. The results show that at the low dose range, of 0 to 12 Gy, which is of importance for the radiation biology and where the effects of exposure to ionizing radiation were not explored in the previously published work, an increase of the dose of ionizing radiation results in an increase of the thermodynamic stability as well as in an increase of the apparent molecular weight of the DNA macromolecules. In all cases conductivity changes precede by a ΔT of about 3°C the helix to coil transition changes, as those are measured by the breakage of the intramolecular hydrogen bonds. This ΔT is independent of the effected molecular weight changes. en
heal.publisher IEEE, Piscataway, NJ, United States en
heal.journalName Proceedings - International Symposium on Electrets en
dc.identifier.doi 10.1109/ISE.1996.578201 en
dc.identifier.spage 747 en
dc.identifier.epage 752 en

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