Morphometric characteristics of red blood cells as diagnostic factors for coronary artery disease

Alexandratou, E; Yova, D; Cokkinos, DV

dc.contributor.author	Alexandratou, E	en
dc.contributor.author	Yova, D	en
dc.contributor.author	Cokkinos, DV	en
dc.date.accessioned	2014-03-01T02:41:36Z
dc.date.available	2014-03-01T02:41:36Z
dc.date.issued	1999	en
dc.identifier.issn	1386-0291	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/30561
dc.relation.uri	http://www.scopus.com/inward/record.url?eid=2-s2.0-0033508688&partnerID=40&md5=8fa60e914b0832d8e5181e6113719790	en
dc.subject.classification	Hematology	en
dc.subject.classification	Peripheral Vascular Disease	en
dc.subject.other	clinical article	en
dc.subject.other	conference paper	en
dc.subject.other	controlled study	en
dc.subject.other	coronary artery disease	en
dc.subject.other	diagnostic value	en
dc.subject.other	erythrocyte	en
dc.subject.other	human	en
dc.subject.other	statistical analysis	en
dc.subject.other	Biological Markers	en
dc.subject.other	Coronary Disease	en
dc.subject.other	Erythrocyte Deformability	en
dc.subject.other	Erythrocytes	en
dc.subject.other	Humans	en
dc.subject.other	Image Enhancement	en
dc.title	Morphometric characteristics of red blood cells as diagnostic factors for coronary artery disease	en
heal.type	conferenceItem	en
heal.language	English	en
heal.publicationDate	1999	en
heal.abstract	Digital imaging microscopy plays an important role in computer aided cytological and histological diagnosis. In this study, digital imaging microscopy was used to measure Red Blood Cells (RBCs) morphometric characteristics such as area, perimeter, major and minor axis length, elongation, compactness and roughness in both groups: healthy individuals and Coronary Artery Disease (CAD) patients. All the measured characteristics, except elongation, showed a statistically significant difference between the two groups. In particular, patients with CAD presented greater values than healthy ones. Finally multivariate analysis was used in order to take into account the whole measured profile of each patient: Compactness, perimeter and elongation improved the diagnostic ability, whereas all the others did not show any significant improvement. These three characteristics correctly classify the 84.5% of the patients. In conclusion, RBCs morphometric characteristics could be considered as diagnostic factors for CAD.	en
heal.publisher	IOS PRESS	en
heal.journalName	Clinical Hemorheology and Microcirculation	en
dc.identifier.isi	ISI:000085524300039	en
dc.identifier.volume	21	en
dc.identifier.issue	3-4	en
dc.identifier.spage	383	en
dc.identifier.epage	388	en