Biocompatible photolithographic process for the patterning of biomolecules

Douvas, A; Argitis, P; Misiakos, K; Dimotikali, D; Petrou, PS; Kakabakos, SE

dc.contributor.author	Douvas, A	en
dc.contributor.author	Argitis, P	en
dc.contributor.author	Misiakos, K	en
dc.contributor.author	Dimotikali, D	en
dc.contributor.author	Petrou, PS	en
dc.contributor.author	Kakabakos, SE	en
dc.date.accessioned	2014-03-01T02:42:04Z
dc.date.available	2014-03-01T02:42:04Z
dc.date.issued	2002	en
dc.identifier.issn	0956-5663	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/30766
dc.subject	Biomolecule	en
dc.subject	Immunoanalysis	en
dc.subject	Photoresist	en
dc.subject.classification	Biophysics	en
dc.subject.classification	Biotechnology & Applied Microbiology	en
dc.subject.classification	Chemistry, Analytical	en
dc.subject.classification	Electrochemistry	en
dc.subject.classification	Nanoscience & Nanotechnology	en
dc.subject.other	Imaging techniques	en
dc.subject.other	Photoresists	en
dc.subject.other	Polystyrenes	en
dc.subject.other	Sensitivity analysis	en
dc.subject.other	Silicon wafers	en
dc.subject.other	Substrates	en
dc.subject.other	Sulfonium salt photoacid generators	en
dc.subject.other	Biomaterials	en
dc.subject.other	acrylic acid derivative	en
dc.subject.other	immunoglobulin G	en
dc.subject.other	poly(tert butylacrylate)	en
dc.subject.other	polystyrene	en
dc.subject.other	silicon	en
dc.subject.other	sulfonium derivative	en
dc.subject.other	unclassified drug	en
dc.subject.other	analytic method	en
dc.subject.other	biocompatibility	en
dc.subject.other	conference paper	en
dc.subject.other	dilution	en
dc.subject.other	generator	en
dc.subject.other	geometry	en
dc.subject.other	imaging	en
dc.subject.other	immunoassay	en
dc.subject.other	molecular recognition	en
dc.subject.other	optical resolution	en
dc.subject.other	pattern recognition	en
dc.subject.other	photolitography	en
dc.subject.other	surface property	en
dc.subject.other	thermal analysis	en
dc.subject.other	Animals	en
dc.subject.other	Coated Materials, Biocompatible	en
dc.subject.other	Feasibility Studies	en
dc.subject.other	Immunoassay	en
dc.subject.other	Immunoglobulin G	en
dc.subject.other	Mice	en
dc.subject.other	Models, Chemical	en
dc.subject.other	Nanotechnology	en
dc.subject.other	Photography	en
dc.subject.other	Polystyrenes	en
dc.subject.other	Sensitivity and Specificity	en
dc.subject.other	Surface Properties	en
dc.title	Biocompatible photolithographic process for the patterning of biomolecules	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1016/S0956-5663(01)00294-9	en
heal.identifier.secondary	http://dx.doi.org/10.1016/S0956-5663(01)00294-9	en
heal.language	English	en
heal.publicationDate	2002	en
heal.abstract	A new approach for the patterning of biomolecule layers is introduced based on the design of a new photoresist material with biocompatible lithographic processing requirements. The photoresist is based on poly(t-butyl acrylate), which allows positive imaging with very dilute basic solutions, tolerable by selected biomolecules used in immunoanalysis. Sensitivity at lambda > 300 nm is obtained using a suitable sulfonium salt photoacid generator. Thermal steps also take place under conditions tolerable by biomolecules. Lithographic results on Si wafer substrates show resolution capabilities for equal lines/spaces, down to the range of 5-10 mum under biocompatible conditions. The process is also used on substrates of different geometries, including inner capillary surfaces. The patterning of the inner surface of a polystyrene capillary with mouse IgG is reported to demonstrate the principles of the above approach. (C) 2002 Elsevier Science B.V. All rights reserved.	en
heal.publisher	ELSEVIER ADVANCED TECHNOLOGY	en
heal.journalName	Biosensors and Bioelectronics	en
dc.identifier.doi	10.1016/S0956-5663(01)00294-9	en
dc.identifier.isi	ISI:000174693300003	en
dc.identifier.volume	17	en
dc.identifier.issue	4	en
dc.identifier.spage	269	en
dc.identifier.epage	278	en