Biocompatible photolithographic process for the patterning of biomolecules

DSpace/Manakin Repository

Show simple item record

dc.contributor.author Douvas, A en
dc.contributor.author Argitis, P en
dc.contributor.author Misiakos, K en
dc.contributor.author Dimotikali, D en
dc.contributor.author Petrou, PS en
dc.contributor.author Kakabakos, SE en
dc.date.accessioned 2014-03-01T02:42:04Z
dc.date.available 2014-03-01T02:42:04Z
dc.date.issued 2002 en
dc.identifier.issn 0956-5663 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/30766
dc.subject Biomolecule en
dc.subject Immunoanalysis en
dc.subject Photoresist en
dc.subject.classification Biophysics en
dc.subject.classification Biotechnology & Applied Microbiology en
dc.subject.classification Chemistry, Analytical en
dc.subject.classification Electrochemistry en
dc.subject.classification Nanoscience & Nanotechnology en
dc.subject.other Imaging techniques en
dc.subject.other Photoresists en
dc.subject.other Polystyrenes en
dc.subject.other Sensitivity analysis en
dc.subject.other Silicon wafers en
dc.subject.other Substrates en
dc.subject.other Sulfonium salt photoacid generators en
dc.subject.other Biomaterials en
dc.subject.other acrylic acid derivative en
dc.subject.other immunoglobulin G en
dc.subject.other poly(tert butylacrylate) en
dc.subject.other polystyrene en
dc.subject.other silicon en
dc.subject.other sulfonium derivative en
dc.subject.other unclassified drug en
dc.subject.other analytic method en
dc.subject.other biocompatibility en
dc.subject.other conference paper en
dc.subject.other dilution en
dc.subject.other generator en
dc.subject.other geometry en
dc.subject.other imaging en
dc.subject.other immunoassay en
dc.subject.other molecular recognition en
dc.subject.other optical resolution en
dc.subject.other pattern recognition en
dc.subject.other photolitography en
dc.subject.other surface property en
dc.subject.other thermal analysis en
dc.subject.other Animals en
dc.subject.other Coated Materials, Biocompatible en
dc.subject.other Feasibility Studies en
dc.subject.other Immunoassay en
dc.subject.other Immunoglobulin G en
dc.subject.other Mice en
dc.subject.other Models, Chemical en
dc.subject.other Nanotechnology en
dc.subject.other Photography en
dc.subject.other Polystyrenes en
dc.subject.other Sensitivity and Specificity en
dc.subject.other Surface Properties en
dc.title Biocompatible photolithographic process for the patterning of biomolecules en
heal.type conferenceItem en
heal.identifier.primary 10.1016/S0956-5663(01)00294-9 en
heal.identifier.secondary http://dx.doi.org/10.1016/S0956-5663(01)00294-9 en
heal.language English en
heal.publicationDate 2002 en
heal.abstract A new approach for the patterning of biomolecule layers is introduced based on the design of a new photoresist material with biocompatible lithographic processing requirements. The photoresist is based on poly(t-butyl acrylate), which allows positive imaging with very dilute basic solutions, tolerable by selected biomolecules used in immunoanalysis. Sensitivity at lambda > 300 nm is obtained using a suitable sulfonium salt photoacid generator. Thermal steps also take place under conditions tolerable by biomolecules. Lithographic results on Si wafer substrates show resolution capabilities for equal lines/spaces, down to the range of 5-10 mum under biocompatible conditions. The process is also used on substrates of different geometries, including inner capillary surfaces. The patterning of the inner surface of a polystyrene capillary with mouse IgG is reported to demonstrate the principles of the above approach. (C) 2002 Elsevier Science B.V. All rights reserved. en
heal.journalName Biosensors and Bioelectronics en
dc.identifier.doi 10.1016/S0956-5663(01)00294-9 en
dc.identifier.isi ISI:000174693300003 en
dc.identifier.volume 17 en
dc.identifier.issue 4 en
dc.identifier.spage 269 en
dc.identifier.epage 278 en

Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record