Monte Carlo calculation of nanoscale dosimetric distributions of MeV proton tracks with secondary electron transport

Emfietzoglou, D; Paganetti, H; Papamichael, G; Pathak, A

dc.contributor.author	Emfietzoglou, D	en
dc.contributor.author	Paganetti, H	en
dc.contributor.author	Papamichael, G	en
dc.contributor.author	Pathak, A	en
dc.date.accessioned	2014-03-01T02:44:06Z
dc.date.available	2014-03-01T02:44:06Z
dc.date.issued	2006	en
dc.identifier.issn	0168-583X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/31679
dc.subject	Microdosimetry	en
dc.subject	Monte Carlo	en
dc.subject	Protons	en
dc.subject	Water	en
dc.subject.classification	Instruments & Instrumentation	en
dc.subject.classification	Nuclear Science & Technology	en
dc.subject.classification	Physics, Atomic, Molecular & Chemical	en
dc.subject.classification	Physics, Nuclear	en
dc.subject.other	Computer simulation	en
dc.subject.other	DNA	en
dc.subject.other	Dosimetry	en
dc.subject.other	Electron transport properties	en
dc.subject.other	Monte Carlo methods	en
dc.subject.other	Targets	en
dc.subject.other	Water	en
dc.subject.other	Chromatin-size targets	en
dc.subject.other	Energy deposition	en
dc.subject.other	Microdosimetry	en
dc.subject.other	Monte Carlo	en
dc.subject.other	Protons	en
dc.title	Monte Carlo calculation of nanoscale dosimetric distributions of MeV proton tracks with secondary electron transport	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1016/j.nimb.2005.11.083	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.nimb.2005.11.083	en
heal.language	English	en
heal.publicationDate	2006	en
heal.abstract	Our MC4 Monte Carlo code which simulates in an event-by-event mode the electronic losses and slowing down process of protons and all their secondary electrons in water is used to obtain dosimetric distributions of interest to the biophysical modelling of proton beams at the submicron scale. Energy loss scattering models constructed from the oscillator strength formalism of Bethe as well as Ritchie's dielectric approach have been implemented in order to explore the influence of non-linear density effects induced by the liquid-like cellular environment. We present results on energy deposition and its straggling for nanometer spherical volumes relevant to DNA- and chromatin-size targets. The influence of the impact geometry and the size of the volume are examined. (c) 2005 Elsevier B.V. All rights reserved.	en
heal.publisher	ELSEVIER SCIENCE BV	en
heal.journalName	Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms	en
dc.identifier.doi	10.1016/j.nimb.2005.11.083	en
dc.identifier.isi	ISI:000236288500018	en
dc.identifier.volume	245	en
dc.identifier.issue	1	en
dc.identifier.spage	80	en
dc.identifier.epage	84	en