Enhancing the focusing properties of a prototype non-invasive brain hyperthermia system: A simulation study

Karathanasis, KT; Karanasiou, IS; Uzunoglu, NK

dc.contributor.author	Karathanasis, KT	en
dc.contributor.author	Karanasiou, IS	en
dc.contributor.author	Uzunoglu, NK	en
dc.date.accessioned	2014-03-01T02:44:36Z
dc.date.available	2014-03-01T02:44:36Z
dc.date.issued	2007	en
dc.identifier.issn	05891019	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/31899
dc.subject	Electric Field	en
dc.subject	Fem Simulation	en
dc.subject	Human Body	en
dc.subject	Left Handed Material	en
dc.subject	Passive Measurement	en
dc.subject	Simulation Study	en
dc.subject	Temperature Distribution	en
dc.subject	Area of Interest	en
dc.subject.other	Computation theory	en
dc.subject.other	Computer simulation	en
dc.subject.other	Problem solving	en
dc.subject.other	Temperature distribution	en
dc.subject.other	Hyperthermia system	en
dc.subject.other	Hyperthermia treatment	en
dc.subject.other	Biomedical engineering	en
dc.title	Enhancing the focusing properties of a prototype non-invasive brain hyperthermia system: A simulation study	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1109/IEMBS.2007.4352262	en
heal.identifier.secondary	http://dx.doi.org/10.1109/IEMBS.2007.4352262	en
heal.identifier.secondary	4352262	en
heal.publicationDate	2007	en
heal.abstract	Aim of this study is the improvement of the focusing properties of a prototype system for deep brain hyperthermia able to provide also passive measurements of temperature distributions inside the human body and especially the brain. One of the main modules of the system which ensures the necessary beamforming and focusing on the body and brain cortex areas of interest is the symmetrical axis ellipsoidal conductive wall cavity. The proposed system operates in a total non-invasive contactless passive manner and is designed to provide hyperthermia treatment and temperature monitoring. Extensive simulations to compute electric field distributions and SAR values at several frequencies inside the human head model and inside the whole ellipsoidal reflector were carried out. One of the main problems that have to be tackled in order to achieve the desired depth and focusing resolution is to reduce back scattering while improving penetration. With this view, the FEM simulations using a commercial tool aimed at improving the system's focusing properties following various approaches. In order to enhance the matching conditions on the air-head interface, layers made of metamaterials (left handed materials) and dielectric materials were placed around the human head model. The results show that the use of a metamaterial layer in conjunction with a layer of lossless dielectric material generates the largest improvement. Measurements using phantoms with the proposed focusing improvement techniques in future studies will complement the present research and reveal the potential practical value of the system. © 2007 IEEE.	en
heal.journalName	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings	en
dc.identifier.doi	10.1109/IEMBS.2007.4352262	en
dc.identifier.volume	2007	en
dc.identifier.spage	218	en
dc.identifier.epage	221	en