FDTD study of the focusing properties of a hybrid hyperthermia and radiometry imaging system using a realistic human head model

Gouzouasis, IA; Karanasiou, IS; Uzunoglu, NK

dc.contributor.author	Gouzouasis, IA	en
dc.contributor.author	Karanasiou, IS	en
dc.contributor.author	Uzunoglu, NK	en
dc.date.accessioned	2014-03-01T02:44:37Z
dc.date.available	2014-03-01T02:44:37Z
dc.date.issued	2007	en
dc.identifier.issn	05891019	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/31913
dc.subject	Biological Tissue	en
dc.subject	Electric Field	en
dc.subject	Focal Point	en
dc.subject	Imaging System	en
dc.subject	Microwave Radiometry	en
dc.subject	Model Development	en
dc.subject.other	Finite difference time domain method	en
dc.subject.other	Hyperthermia therapy	en
dc.subject.other	Magnetic resonance imaging	en
dc.subject.other	Mammals	en
dc.subject.other	Physiological models	en
dc.subject.other	Radiometry	en
dc.subject.other	Ellipsoidal conductive wall cavity	en
dc.subject.other	Radiometry tomography systems	en
dc.subject.other	Imaging systems	en
dc.title	FDTD study of the focusing properties of a hybrid hyperthermia and radiometry imaging system using a realistic human head model	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1109/IEMBS.2007.4353098	en
heal.identifier.secondary	http://dx.doi.org/10.1109/IEMBS.2007.4353098	en
heal.identifier.secondary	4353098	en
heal.publicationDate	2007	en
heal.abstract	Aim of this study is twofold; on one hand, the investigation of the focusing attributes of a microwave radiometry tomography system with the use of a realistic human head model and on the other hand, the system's ability to perform a hyperthermia treatment. The operation principle of the device is based on an ellipsoidal conductive wall cavity, which provides the required beamforming and focusing. The biological tissue under treatment and/or measurement is placed on one of the two focal points whereas on the other one, a radiating or receiving antenna, which measures the black body type radiation emitted from the head's tissue, is placed. In previous studies simple spherical head models were used, comprising one or two layers for simulating the head tissues, along with a commercial FEM tool. In this work, a realistic adult head model developed from MRI scans of a human head is used. The realistic model with detailed structural and electromagnetic tissue characteristics enables more in depth theoretical investigation of the system capabilities. Extensive simulations using a commercial FDTD tool are performed in a wide range of operating frequencies. In order to explore the feasibility of heating and monitoring specific brain areas, the capability of focusing the electric field in specific areas inside the human head is investigated and further discussed. The results show that simple spherical head models, used in previous studies, provide similar results with the realistic one used herein for the given geometry; that is, the electric field focuses on the head's center, assuming the head as a homogeneous sphere. However, the deposition of the electromagnetic energy on the head tissues depends on the operating frequency and position of the head in the given geometry, so is therefore calculated, revealing the ability of the system to operate as a hyperthermia clinical tool, not as a stand alone device but in conjunction with other already validated devices/methods. © 2007 IEEE.	en
heal.journalName	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings	en
dc.identifier.doi	10.1109/IEMBS.2007.4353098	en
dc.identifier.volume	2007	en
dc.identifier.spage	3552	en
dc.identifier.epage	3555	en