Enzymatic transformation of flavonoids and terpenoids: Structural and functional diversity of the novel derivatives

Xanthakis, E; Theodosiou, E; Magkouta, S; Stamatis, H; Loutrari, H; Roussos, C; Kolisis, F

dc.contributor.author	Xanthakis, E	en
dc.contributor.author	Theodosiou, E	en
dc.contributor.author	Magkouta, S	en
dc.contributor.author	Stamatis, H	en
dc.contributor.author	Loutrari, H	en
dc.contributor.author	Roussos, C	en
dc.contributor.author	Kolisis, F	en
dc.date.accessioned	2014-03-01T02:46:47Z
dc.date.available	2014-03-01T02:46:47Z
dc.date.issued	2010	en
dc.identifier.issn	0033-4545	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/32848
dc.subject	Anti-tumoractivity	en
dc.subject	Biocatalysis	en
dc.subject	Flavonoids	en
dc.subject	Phytochemicals	en
dc.subject	Terpenoids	en
dc.subject.classification	Chemistry, Multidisciplinary	en
dc.subject.other	CANDIDA-ANTARCTICA LIPASE	en
dc.subject.other	POLYHYDROXYLATED NATURAL COMPOUNDS	en
dc.subject.other	REGIOSELECTIVE ACYLATION	en
dc.subject.other	IONIC LIQUIDS	en
dc.subject.other	PERILLYL ALCOHOL	en
dc.subject.other	PHENOLIC-ACIDS	en
dc.subject.other	FATTY-ACIDS	en
dc.subject.other	CATALYZED ESTERIFICATION	en
dc.subject.other	CHEMOENZYMATIC SYNTHESIS	en
dc.subject.other	BIOCATALYTIC PREPARATION	en
dc.title	Enzymatic transformation of flavonoids and terpenoids: Structural and functional diversity of the novel derivatives	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1351/PAC-CON-09-01-19	en
heal.identifier.secondary	http://dx.doi.org/10.1351/PAC-CON-09-01-19	en
heal.language	English	en
heal.publicationDate	2010	en
heal.abstract	Flavonoids and terpenoids are promising candidates for use as functional foods and novel therapeutics due to their prominent biological activities. However, the use of several bioactive plant compounds is limited by low stability and solubility problems. This review underlines the feasibility of enzymatic synthesis of novel bioactive analogs of selected flavonoids (silybin, rutin) and terpenoids (perillyl alcohol, POH) in nonconventional reaction systems. The effect of various parameters on the enzymatic acylation and/or glucosylation of these phytochemicals was studied. Also, the role of the structure of the novel molecules in relation to their biological function was investigated in various cancer cell lines. © 2010 IUPAC.	en
heal.publisher	INT UNION PURE APPLIED CHEMISTRY	en
heal.journalName	Pure and Applied Chemistry	en
dc.identifier.doi	10.1351/PAC-CON-09-01-19	en
dc.identifier.isi	ISI:000274709300002	en
dc.identifier.volume	82	en
dc.identifier.issue	1	en
dc.identifier.spage	1	en
dc.identifier.epage	16	en