Colon cancer diagnosis using fluorescence spectroscopy and fluorescence imaging tecnique

Yova, D; Atlamazoglou, V; Davaris, P; Kavantzas, N; Loukas, S

dc.contributor.author	Yova, D	en
dc.contributor.author	Atlamazoglou, V	en
dc.contributor.author	Davaris, P	en
dc.contributor.author	Kavantzas, N	en
dc.contributor.author	Loukas, S	en
dc.date.accessioned	2014-03-01T02:48:30Z
dc.date.available	2014-03-01T02:48:30Z
dc.date.issued	1997	en
dc.identifier.issn	0277786X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/33871
dc.subject	Autofluorescence	en
dc.subject	Colon cancer	en
dc.subject	Fluorescence imaging	en
dc.subject	Fluorescence spectroscopy	en
dc.subject	Optical diagnostics	en
dc.subject.other	Diagnosis	en
dc.subject.other	Fluorescence	en
dc.subject.other	Spectroscopic analysis	en
dc.subject.other	Synthesis (chemical)	en
dc.subject.other	Tumors	en
dc.subject.other	Autofluorescence	en
dc.subject.other	Colon cancers	en
dc.subject.other	Medical imaging	en
dc.title	Colon cancer diagnosis using fluorescence spectroscopy and fluorescence imaging tecnique	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1117/12.297946	en
heal.identifier.secondary	http://dx.doi.org/10.1117/12.297946	en
heal.publicationDate	1997	en
heal.abstract	It is well known that fluorescence spectroscopy can provide information about the differences in the concentration of chromophores in healthy and cancerous tissues. The tumor detection potential can be enhanced by using exogenous fluorescent agents with selective accumulation in cancerous tissue. In this study healthy and cancerous human colon tissue samples were obtained after colon surgery. Excitation Emission Matrices were collected using a fluorescence spectrometer. The optimum excitation wavelength lied at 340 nm. After the acquisition of autofluorescence spectra, the samples were incubated in a solution of 4 μg/ml of Rhodamine analogs. Rhodamine B, Rhodamine 6G and three recently synthesized analogs, were used. For the acqusition of fluorescence images, an endoscopic imaging system was developed. Fluorescence imaging with the concominant use of Rhodamine analogs revealed a remarkable differentiation of cancerous from healthy colonic mucosa.	en
heal.journalName	Proceedings of SPIE - The International Society for Optical Engineering	en
dc.identifier.doi	10.1117/12.297946	en
dc.identifier.volume	3197	en
dc.identifier.spage	4	en
dc.identifier.epage	15	en