A diffusion approximation model of light transport in multilayered skin tissue

Makropoulou, M; Kaselouris, E; Drakaki, E; Serafetinides, AA; Sianoudis, JA

dc.contributor.author	Makropoulou, M	en
dc.contributor.author	Kaselouris, E	en
dc.contributor.author	Drakaki, E	en
dc.contributor.author	Serafetinides, AA	en
dc.contributor.author	Sianoudis, JA	en
dc.date.accessioned	2014-03-01T02:51:01Z
dc.date.available	2014-03-01T02:51:01Z
dc.date.issued	2007	en
dc.identifier.issn	16057422	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/35294
dc.relation.uri	http://www.scopus.com/inward/record.url?eid=2-s2.0-36249031969&partnerID=40&md5=3cafe00fa4088cea4c7afda686316657	en
dc.subject	Diffuse reflectance spectroscopy	en
dc.subject	Diffusion approximation theory	en
dc.subject	Laser induced fluorescence	en
dc.subject.other	Approximation theory	en
dc.subject.other	Dermatology	en
dc.subject.other	Diffusion	en
dc.subject.other	Sensitivity analysis	en
dc.subject.other	Skin	en
dc.subject.other	Tissue	en
dc.subject.other	Diffuse reflectance spectroscopy	en
dc.subject.other	Diffusion approximation theory	en
dc.subject.other	Laser induced fluorescence	en
dc.subject.other	Multilayered skin tissue	en
dc.subject.other	Light transmission	en
dc.title	A diffusion approximation model of light transport in multilayered skin tissue	en
heal.type	conferenceItem	en
heal.identifier.secondary	662818	en
heal.publicationDate	2007	en
heal.abstract	In dermatology, biophotonic methods offer high sensitivity and non-invasive measurements of skin tissue optical properties, in various physiological and pathological conditions. There are numerous skin processes, which can be examined and characterized using diagnostic optical spectroscopy, as the monitoring of skin aging, diagnosis of benign and malignant cutaneous lesions, dosimetry in photodynamic therapy (PDT), etc. Several mathematical models have been used to calculate the tissue optical properties from experimental measurements and to predict the light propagation in soft tissues, like skin, based on transport theory or Monte Carlo modeling. This work analyses the phenomena which are observed experimentally during the irradiation of skin, such as the absorption, reflectance, scattering, fluorescence and transmission of laser light. The study was carried out on animal skin samples, extracted post-mortem. In this work we also tried to evaluate the utility of diffusion approximation modeling for measuring the light intensity distribution in the skin samples with cw visible laser beam (λ=632.8 nm). The diffusion theory model was tested for the simulation results of the spatial light distribution within a five-layer model of animal skin tissue. We have studied the dependence towards the depth and the radial distance of the photon density of the incident radiation. © 2007 SPIE-OSA.	en
heal.journalName	Progress in Biomedical Optics and Imaging - Proceedings of SPIE	en
dc.identifier.volume	6628	en