Optical spectroscopic studies of animal skin used in modelling of human cutaneous tissue

Drakaki, E; Makropoulou, M; Serafetinides, AA; Borisova, E; Avramov, L; Sianoudis, JA

dc.contributor.author	Drakaki, E	en
dc.contributor.author	Makropoulou, M	en
dc.contributor.author	Serafetinides, AA	en
dc.contributor.author	Borisova, E	en
dc.contributor.author	Avramov, L	en
dc.contributor.author	Sianoudis, JA	en
dc.date.accessioned	2014-03-01T02:51:08Z
dc.date.available	2014-03-01T02:51:08Z
dc.date.issued	2007	en
dc.identifier.issn	0277786X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/35398
dc.subject	Animal model	en
dc.subject	Diffuse reflectance spectroscopy	en
dc.subject	Human skins	en
dc.subject	Laser-induced fluorescence spectroscopy	en
dc.subject.other	Emission spectroscopy	en
dc.subject.other	Fluorescence spectroscopy	en
dc.subject.other	Laser applications	en
dc.subject.other	Pathology	en
dc.subject.other	Animal model	en
dc.subject.other	Diffuse reflectance spectroscopy (DRS)	en
dc.subject.other	Laser sources	en
dc.subject.other	Laser-induced autofluorescence spectroscopy (LIAFS)	en
dc.subject.other	Skin	en
dc.title	Optical spectroscopic studies of animal skin used in modelling of human cutaneous tissue	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1117/12.727723	en
heal.identifier.secondary	http://dx.doi.org/10.1117/12.727723	en
heal.identifier.secondary	66042K	en
heal.publicationDate	2007	en
heal.abstract	Optical spectroscopy and in particular laser-induced autofluorescence spectroscopy (LIAFS) and diffuse reflectance spectroscopy (DRS), provide excellent possibilities for real-time, noninvasive diagnosis of different skin tissue pathologies. However, the introduction of optical spectroscopy in routine medical practice demands a statistically important data collection, independent from the laser sources and detectors used. The scientists collect databases either from patients, in vivo, or they study different animal models to obtain objective information for the optical properties of various types of normal and diseased tissue. In the present work, the optical properties (fluorescence and reflectance) of two animal skin models are investigated. The aim of using animal models in optical spectroscopy investigations is to examine the statistics of the light induced effects firstly on animals, before any extrapolation effort to humans. A nitrogen laser (λ.=337.1 nm) was used as an excitation source for the autofluorescence measurements, while a tungstenhalogen lamp was used for the reflectance measurements. Samples of chicken and pig skin were measured in vitro and were compared with results obtained from measurements of normal human skin in vivo. The specific features of the measured reflectance and fluorescence spectra are discussed, while the limits of data extrapolation for each skin type are also depicted.	en
heal.journalName	Proceedings of SPIE - The International Society for Optical Engineering	en
dc.identifier.doi	10.1117/12.727723	en
dc.identifier.volume	6604	en