Synchrotron FT-IR spectroscopy of human bones. The effect of aging

Kolovou, P; Anastassopoulou, J

dc.contributor.author	Kolovou, P	en
dc.contributor.author	Anastassopoulou, J	en
dc.date.accessioned	2014-03-01T02:51:16Z
dc.date.available	2014-03-01T02:51:16Z
dc.date.issued	2007	en
dc.identifier.issn	1871465X	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/35438
dc.subject	Human bone	en
dc.subject	Irradiation	en
dc.subject	Micro-FT-IR	en
dc.subject	Spectroscopy	en
dc.subject	Synchrotron	en
dc.title	Synchrotron FT-IR spectroscopy of human bones. The effect of aging	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1007/978-1-4020-5724-3-24	en
heal.identifier.secondary	http://dx.doi.org/10.1007/978-1-4020-5724-3-24	en
heal.publicationDate	2007	en
heal.abstract	The Synchrotron micro-FT-IR spectroscopy was used to investigate the structural changes of human bones, which are produced upon irradiation. It was observed that after irradiation with a dose of 40 Gy up to 119 Gy the band at 1660 cm-1, which corresponds to the absorption of the Amide I group (-NH-CO-) and indicates that the collagen exists in α-helix, shows considerable changes upon irradiation resulting that the collagen looses its structure from α-helix to random coil. Considerable changes were also observed in the region of the spectra between 900 cm-1 and 1200 cm-1 where the phosphate groups (v3PO43-) of hydroxyapatite absorb. These bands change in intensity and shape. These findings show that the irradiation of human bones leads to damage of the main components of bone tissues. © 2007 Springer.	en
heal.journalName	NATO Security through Science Series B: Physics and Biophysics	en
dc.identifier.doi	10.1007/978-1-4020-5724-3-24	en
dc.identifier.spage	267	en
dc.identifier.epage	272	en