Computational study of an augmented minimal model for glycaemia control

Markakis, MG; Mitsis, GD; Marmarelis, VZ

dc.contributor.author	Markakis, MG	en
dc.contributor.author	Mitsis, GD	en
dc.contributor.author	Marmarelis, VZ	en
dc.date.accessioned	2014-03-01T02:51:34Z
dc.date.available	2014-03-01T02:51:34Z
dc.date.issued	2008	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/35567
dc.relation.uri	http://www.scopus.com/inward/record.url?eid=2-s2.0-61849085227&partnerID=40&md5=37c36812fb0fff1a9e9a7a4568ebaa15	en
dc.subject.other	Blood glucose	en
dc.subject.other	Computational studies	en
dc.subject.other	Healthy subjects	en
dc.subject.other	Metabolic effects	en
dc.subject.other	Minimal models	en
dc.subject.other	New models	en
dc.subject.other	New structures	en
dc.subject.other	Non-linear models	en
dc.subject.other	Non-parametric	en
dc.subject.other	Parameter values	en
dc.subject.other	Principal dynamic modes	en
dc.subject.other	Glucose	en
dc.subject.other	Insulin	en
dc.title	Computational study of an augmented minimal model for glycaemia control	en
heal.type	conferenceItem	en
heal.identifier.secondary	4650446	en
heal.publicationDate	2008	en
heal.abstract	In this paper we introduce a new model structure for the metabolic effects of intravenous insulin on blood glucose in man and derive its parameter values from the widely used model of Sorensen. The proposed model attempts to combine the advantages of the existing comprehensive and minimal models. Validation of the new model is done through deriving equivalent nonparametric nonlinear models in the form of Principal Dynamic Modes. We show that the new structure can represent the insulin - glucose dynamics of healthy subjects as well as Type 1 and Type 2 diabetics, with appropriate adjustment in its parameters. © 2008 IEEE.	en
heal.journalName	Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - ""Personalized Healthcare through Technology""	en
dc.identifier.spage	5445	en
dc.identifier.epage	5448	en