An epidemiological population study reveals a sex-related differential effect of PAD exposure and gene polymorphisms on bulky DNA adducts formation

Ladoukakis, E; Georgiadis, P; Chatziioannou, A

dc.contributor.author	Ladoukakis, E	en
dc.contributor.author	Georgiadis, P	en
dc.contributor.author	Chatziioannou, A	en
dc.date.accessioned	2014-03-01T02:52:33Z
dc.date.available	2014-03-01T02:52:33Z
dc.date.issued	2010	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/35930
dc.subject.other	Biological effects	en
dc.subject.other	Biologically effective dose	en
dc.subject.other	Cytochrome p450	en
dc.subject.other	Differential effect	en
dc.subject.other	DNA adducts	en
dc.subject.other	Epidemiological studies	en
dc.subject.other	Gene polymorphism	en
dc.subject.other	General population	en
dc.subject.other	Urban air	en
dc.subject.other	Air pollution	en
dc.subject.other	DNA	en
dc.subject.other	Genes	en
dc.subject.other	Nucleic acids	en
dc.subject.other	Polymorphism	en
dc.subject.other	Information technology	en
dc.title	An epidemiological population study reveals a sex-related differential effect of PAD exposure and gene polymorphisms on bulky DNA adducts formation	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1109/ITAB.2010.5687782	en
heal.identifier.secondary	http://dx.doi.org/10.1109/ITAB.2010.5687782	en
heal.identifier.secondary	5687782	en
heal.publicationDate	2010	en
heal.abstract	DNA adducts have been recognized by many studies as biologically effective dose markers of exposure to carcinogen substances. In this epidemiological study, 194 inhabitants of two Greek cities, Athens and Dalkida, are examined in order to investigate the quantitative relationships between exposure of the general population to urban air pollutants such as PADs and various biomarkers of exposure, susceptibility and early biological effects. This study supports a sex-related differential effect of PAD exposure with respect to the implication of given cytochrome P450 enzyme family gene polymorphisms on bulky DNA adducts formation. © 2010 IEEE.	en
heal.journalName	Proceedings of the IEEE/EMBS Region 8 International Conference on Information Technology Applications in Biomedicine, ITAB	en
dc.identifier.doi	10.1109/ITAB.2010.5687782	en