Surface characterization of collagen films by atomic force microscopy

Stylianou, A; Kontomaris, SB; Kyriazi, M; Yova, D

dc.contributor.author	Stylianou, A	en
dc.contributor.author	Kontomaris, SB	en
dc.contributor.author	Kyriazi, M	en
dc.contributor.author	Yova, D	en
dc.date.accessioned	2014-03-01T02:52:46Z
dc.date.available	2014-03-01T02:52:46Z
dc.date.issued	2010	en
dc.identifier.issn	16800737	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/36053
dc.subject	Atomic Force Microscopy	en
dc.subject	Collagen Films	en
dc.subject	Nanobiomaterials	en
dc.subject	Nanomanipulation	en
dc.subject	Roughness	en
dc.subject.other	AFM	en
dc.subject.other	AFM tip	en
dc.subject.other	Angiogenesis	en
dc.subject.other	Biological reaction	en
dc.subject.other	Biological surfaces	en
dc.subject.other	Cell migration	en
dc.subject.other	Cell morphology	en
dc.subject.other	Cellular process	en
dc.subject.other	Collagen Films	en
dc.subject.other	Collagen structure	en
dc.subject.other	Cytoxicity	en
dc.subject.other	Extracellular matrix protein	en
dc.subject.other	Nano-structured	en
dc.subject.other	Nanobiomaterials	en
dc.subject.other	Nanomanipulations	en
dc.subject.other	Roughness	en
dc.subject.other	Specific surface	en
dc.subject.other	Surface characterization	en
dc.subject.other	Tissue repair	en
dc.subject.other	Tissue scaffolding	en
dc.subject.other	Adhesion	en
dc.subject.other	Atomic force microscopy	en
dc.subject.other	Atoms	en
dc.subject.other	Biochemical engineering	en
dc.subject.other	Biocompatibility	en
dc.subject.other	Cell adhesion	en
dc.subject.other	Medical applications	en
dc.subject.other	Medical computing	en
dc.subject.other	Micromanipulators	en
dc.subject.other	Nanotechnology	en
dc.subject.other	Surface properties	en
dc.subject.other	Surface reactions	en
dc.subject.other	Thin films	en
dc.subject.other	Tissue	en
dc.subject.other	Collagen	en
dc.title	Surface characterization of collagen films by atomic force microscopy	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1007/978-3-642-13039-7_154	en
heal.identifier.secondary	http://dx.doi.org/10.1007/978-3-642-13039-7_154	en
heal.publicationDate	2010	en
heal.abstract	Collagen is the most abundant extracellular matrix protein and is important for a variety of functions, including tissue scaffolding, cell adhesion, cell migration, angiogenesis, tissue morphogenesis and tissue repair. Collagen is considered as one of the most useful biomaterials since it is hydrophilic, exhibits negligible cytoxicity, good hemostatic properties and is readily available and biocompatible. As the majority of the biological reactions occurs on surfaces or interfaces it is of great importance to nanostructure the collagen thin film. These films are useful to address a variety of biological issues, including cell morphology and the influence of surface properties on intacellural signaling and can be used to cover non-biological surfaces offering them biocompatibility. In this paper thin films of collagen were formed and according to the used methodology different collagen structures were created. The atomic force microscopy enabled the observation of the different patterns and the measurement of specific surface characteristics. Additionally, the AFM tip was used to nanomanipulate the collagen structure in the air. The AFM topographs showed that differently nanostructured collagen films were formed with pre-determided characteristics. These films can be used to direct cellular processes in a variety of research and later medical applications. © 2010 International Federation for Medical and Biological Engineering.	en
heal.journalName	IFMBE Proceedings	en
dc.identifier.doi	10.1007/978-3-642-13039-7_154	en
dc.identifier.volume	29	en
dc.identifier.spage	612	en
dc.identifier.epage	615	en