Selective immobilization of proteins guided by photo-patterned poly(vinyl alcohol) structures

Pavli, P; Petrou, PS; Douvas, AM; Makarona, E; Kakabakos, S; Dimotikali, D; Argitis, P

dc.contributor.author	Pavli, P	en
dc.contributor.author	Petrou, PS	en
dc.contributor.author	Douvas, AM	en
dc.contributor.author	Makarona, E	en
dc.contributor.author	Kakabakos, S	en
dc.contributor.author	Dimotikali, D	en
dc.contributor.author	Argitis, P	en
dc.date.accessioned	2014-03-01T02:53:27Z
dc.date.available	2014-03-01T02:53:27Z
dc.date.issued	2011	en
dc.identifier.issn	18777058	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/36335
dc.subject	12-phosphotungstic acid	en
dc.subject	Non-fouling materials	en
dc.subject	Photolithography	en
dc.subject	Poly(vinyl alcohol)	en
dc.subject.other	12-Phosphotungstic acid	en
dc.subject.other	Bioelectronic device	en
dc.subject.other	Entropy effects	en
dc.subject.other	Nonfouling	en
dc.subject.other	Protein adsorption	en
dc.subject.other	Protein patterning	en
dc.subject.other	PVA-based	en
dc.subject.other	Selective immobilization	en
dc.subject.other	Van Der Waals interactions	en
dc.subject.other	Hydrogen bonds	en
dc.subject.other	Photolithography	en
dc.subject.other	Physisorption	en
dc.subject.other	Polyvinyl alcohols	en
dc.subject.other	Styrene	en
dc.subject.other	Van der Waals forces	en
dc.subject.other	Proteins	en
dc.title	Selective immobilization of proteins guided by photo-patterned poly(vinyl alcohol) structures	en
heal.type	conferenceItem	en
heal.identifier.primary	10.1016/j.proeng.2011.12.072	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.proeng.2011.12.072	en
heal.publicationDate	2011	en
heal.abstract	The development of ""protein resistant"" materials is challenging since protein physisorption takes place on most surfaces due to van der Waals interactions, hydrogen bonding and entropy effects. In this work a new process for converting a surface resistant to protein adsorption is presented by using a photo-patternable poly(vinyl alcohol) (PVA) based film. This material minimizes effectively protein physisorption and it can be patterned through photolithography on top of any substrate. Herein the PVA-based film is patterned on top of a poly(styrene) (PS) film, in order to achieve selective protein patterning on the PS film and demonstrate the resistance of the PVA-based material to protein physisorption. The proposed methodology is expected to facilitate the fabrication of sensors and bioelectronic devices since it provides a patterning route with alignment capabilities for protein resistant-surfaces and it is based on an easy to implement process. © 2011 Published by Elsevier Ltd.	en
heal.journalName	Procedia Engineering	en
dc.identifier.doi	10.1016/j.proeng.2011.12.072	en
dc.identifier.volume	25	en
dc.identifier.spage	292	en
dc.identifier.epage	295	en