Design and development of a biosensor for the rapid detection of SARS-CoV-2 (en) (el) (el)

Γεωργάς, Αντώνιος; Georgas, Antonios

dc.contributor.author	Γεωργάς, Αντώνιος	el
dc.contributor.author	Georgas, Antonios	en
dc.date.accessioned	2023-03-06T10:15:24Z
dc.date.available	2023-03-06T10:15:24Z
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/57207
dc.identifier.uri	http://dx.doi.org/10.26240/heal.ntua.24905
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ελλάδα	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/gr/	*
dc.subject	Βιοαισθητήρας	el
dc.subject	Κορονοϊός	el
dc.subject	Χωρητικός αισθητήρας	el
dc.subject	Ενδοδιαπλεκόμενα ηλεκτρόδια	el
dc.subject	Ηλεκτρονικό κύκλωμα ανάγνωσης	el
dc.subject	Biosensor	en
dc.subject	SARS-CoV-2	el
dc.subject	Capacitive sensor	el
dc.subject	Interdigitated electrodes	el
dc.subject	Eeadout circuit	el
dc.title	Design and development of a biosensor for the rapid detection of SARS-CoV-2 (en) (el) (el)	el
heal.type	doctoralThesis	el
heal.secondaryTitle	Σχεδίαση και ανάπτυξη βιοαισθητήρα για την ταχεία ανίχνευση του SARS-CoV-2	el
heal.classification	Bioengineering	en
heal.classification	Biosensors	el
heal.language	en	el
heal.access	free	el
heal.recordProvider	ntua	el
heal.publicationDate	2022-11-28
heal.abstract	The aim of this thesis is the development of an electrochemical biosensor for the rapid detection of SARS-CoV-2 in biological samples. In the first part of the thesis, the sensing element is developed, based on the immobilization of the natural receptor of the virus, the enzyme ACE2, on the surface of interdigitated electrode capacitors. The results of the biosensor measurements are correlated with the real-time PCR results for the same samples. Then, after the sensor has been verified to function properly, the sensor is integrated into a lab-developed portable device. This device consists of a custom precision electronic circuit that performs impedance measurements. Also, using Bluetooth, the device wirelessly transmits the measurement results to an android mobile application developed in the framework of the thesis. The final stage concerns the packaging of the biosensor and the electronic device, but also the construction of the connector between the two. The packaging of the device and the manufacturing of the connector are done using 3D printing. The packaging of the biosensor is carried out using a photosensitive film, ORDYL SY 300, which is processed by the method of optical lithography.	en
heal.advisorName	Χριστοφόρου, Ευάγγελος	el
heal.advisorName	Hristoforou, Evangelos	en
heal.committeeMemberName	Χριστοφόρου, Ευάγγελος	el
heal.committeeMemberName	Trifiletti, Alessandro	en
heal.committeeMemberName	Ματσόπουλος, Γεώργιος	el
heal.committeeMemberName	Κουτσούρης, Δημήτριος Διονύσιος	el
heal.committeeMemberName	Γκόνος, Ιωάννης	el
heal.committeeMemberName	Τσανάκας, Παναγιώτης	el
heal.committeeMemberName	Ματίκας, Θεόδωρος	el
heal.academicPublisher	Εθνικό Μετσόβιο Πολυτεχνείο. Σχολή Ηλεκτρολόγων Μηχανικών και Μηχανικών Υπολογιστών	el
heal.academicPublisherID	ntua	el
heal.fullTextAvailability	false