Προσομοίωση δέσμης ηλεκτρονίων σε γραμμικό επιταχυντή για ακτινοθεραπεία FLASH

Ράγγος, Βασίλειος; Rangos, Vasileios

dc.contributor.author	Ράγγος, Βασίλειος	el
dc.contributor.author	Rangos, Vasileios	en
dc.date.accessioned	2025-01-24T11:29:05Z
dc.date.available	2025-01-24T11:29:05Z
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/60949
dc.identifier.uri	http://dx.doi.org/10.26240/heal.ntua.28645
dc.rights	Αναφορά Δημιουργού-Μη Εμπορική Χρήση-Όχι Παράγωγα Έργα 3.0 Ελλάδα	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/3.0/gr/	*
dc.subject	Linear Accelerator	en
dc.subject	Radiotherapy	en
dc.subject	FLASH-RT	en
dc.subject	Ionizing Radiation	en
dc.subject	DNA Damage	en
dc.subject	Γραμμικός Επιταχυντής	el
dc.subject	Ακτινοθεραπεία	el
dc.subject	Βλάβες DNA	el
dc.subject	Ιονίζουσες Ακτινοβολίες	el
dc.subject	Προσομοίωση	el
dc.title	Προσομοίωση δέσμης ηλεκτρονίων σε γραμμικό επιταχυντή για ακτινοθεραπεία FLASH	el
dc.title	Electron beam simulation in linear accelerators for FLASH radiotherapy	en
heal.type	bachelorThesis
heal.classification	Medical Physics	en
heal.classification	Radiation Physics	en
heal.classification	Ιατρική Φυσική	el
heal.classification	Ακτινοφυσική	el
heal.language	en
heal.access	free
heal.recordProvider	ntua	el
heal.publicationDate	2024-09-20
heal.abstract	To enhance the efficiency of radiotherapy in targeting cancerous cells, various methods are employed. FLASH radiotherapy (FLASH-RT), which delivers dose rates greater than 40 Gy/s, has shown a potential to significantly reduce damage to normal tissues while maintaining effectiveness in destroying tumors compared to conventional techniques. The objective of this thesis is to simulate the beam dynamics within the accel erating structure of a linear accelerator, that will be able to deliver high charge density electrons in order to achieve ultra high dose rates required for FLASH-RT. This study will examine the impact of different parameters regarding the ac celerator structure to the output beam and see the behavior of the beam inside the waveguide. Space charge effects must be taken into consideration, as the high charge density of the beam leads to expansion due to internal electromagnetic forces. Dose and dose rate will be approximated as well. Finally, there will be an attempt to simulate DNA damage by FLASH irradi ation using a Monte Carlo simulation. This will take into account assumptions about the environment of the irradiated site and indirectly approximate DNA lesions for both protons and electrons.	en
heal.advisorName	Γεωργακίλας, Αλέξανδρος	el
heal.committeeMemberName	Γεωργακίλας, Αλέξανδρος	el
heal.committeeMemberName	Γαζής, Ευάγγελος	el
heal.committeeMemberName	Κοψαλής, Ιωάννης	el
heal.academicPublisher	Εθνικό Μετσόβιο Πολυτεχνείο. Σχολή Εφαρμοσμένων Μαθηματικών και Φυσικών Επιστημών. Τομέας Φυσικής	el
heal.academicPublisherID	ntua
heal.numberOfPages	88 σ.	el
heal.fullTextAvailability	false