Capacitive microsystems for biological sensing

Tsouti, V; Boutopoulos, C; Zergioti, I; Chatzandroulis, S

dc.contributor.author	Tsouti, V	en
dc.contributor.author	Boutopoulos, C	en
dc.contributor.author	Zergioti, I	en
dc.contributor.author	Chatzandroulis, S	en
dc.date.accessioned	2014-03-01T11:45:10Z
dc.date.available	2014-03-01T11:45:10Z
dc.date.issued	2011	en
dc.identifier.issn	0956-5663	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/37263
dc.subject	Biomolecular interactions	en
dc.subject	Biosensors	en
dc.subject	Capacitive detection	en
dc.subject	Micro-electrodes	en
dc.subject	Micro-membranes	en
dc.subject.classification	Biophysics	en
dc.subject.classification	Biotechnology & Applied Microbiology	en
dc.subject.classification	Chemistry, Analytical	en
dc.subject.classification	Electrochemistry	en
dc.subject.classification	Nanoscience & Nanotechnology	en
dc.subject.other	Advanced diagnostics	en
dc.subject.other	Antigen-antibody binding	en
dc.subject.other	Biological applications	en
dc.subject.other	Biological sensing	en
dc.subject.other	Biomolecular interactions	en
dc.subject.other	Capacitive biosensors	en
dc.subject.other	Capacitive detection	en
dc.subject.other	Classical methods	en
dc.subject.other	DNA hybridization	en
dc.subject.other	Early detection	en
dc.subject.other	Label free	en
dc.subject.other	Micro-membranes	en
dc.subject.other	Operation principles	en
dc.subject.other	Personalized medicines	en
dc.subject.other	Portable device	en
dc.subject.other	Surface stress	en
dc.subject.other	Biosensors	en
dc.subject.other	Electrodes	en
dc.subject.other	Microsystems	en
dc.subject.other	artificial membrane	en
dc.subject.other	biosensor	en
dc.subject.other	capacitive membrane	en
dc.subject.other	capacitive microsystem	en
dc.subject.other	DNA determination	en
dc.subject.other	DNA microarray	en
dc.subject.other	electric capacitance	en
dc.subject.other	electrode	en
dc.subject.other	equipment design	en
dc.subject.other	interdigitated electrode	en
dc.subject.other	microelectrode	en
dc.subject.other	microelectromechanical system	en
dc.subject.other	microtechnology	en
dc.subject.other	molecular interaction	en
dc.subject.other	nonhuman	en
dc.subject.other	review	en
dc.subject.other	solution and solubility	en
dc.subject.other	surface stress	en
dc.subject.other	Biosensing Techniques	en
dc.subject.other	Electric Capacitance	en
dc.subject.other	Humans	en
dc.subject.other	Miniaturization	en
dc.title	Capacitive microsystems for biological sensing	en
heal.type	other	en
heal.identifier.primary	10.1016/j.bios.2011.05.047	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.bios.2011.05.047	en
heal.language	English	en
heal.publicationDate	2011	en
heal.abstract	The growing interest in personalized medicine leads to the need for fast, cheap and portable devices that reveal the genetic profile easily and accurately. To this direction, several ideas to avoid the classical methods of diagnosis and treatment through miniaturized and label-free systems have emerged. Capacitive biosensors address these requirements and thus have the perspective to be used in advanced diagnostic devices that promise early detection of potential fatal conditions. The operation principles, as well as the design and fabrication of several capacitive microsystems for the detection of biomolecular interactions are presented in this review. These systems are micro-membranes based on surface stress changes, interdigitated micro-electrodes and electrode-solution interfaces. Their applications extend to DNA hybridization, protein-ligand binding, antigen-antibody binding, etc. Finally, the limitations and prospects of capacitive microsystems in biological applications are discussed. (C) 2011 Elsevier B.V. All rights reserved.	en
heal.publisher	ELSEVIER ADVANCED TECHNOLOGY	en
heal.journalName	Biosensors and Bioelectronics	en
dc.identifier.doi	10.1016/j.bios.2011.05.047	en
dc.identifier.isi	ISI:000295953300001	en
dc.identifier.volume	27	en
dc.identifier.issue	1	en
dc.identifier.spage	1	en
dc.identifier.epage	11	en