Capacitive microsystems for biological sensing

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dc.contributor.author Tsouti, V en
dc.contributor.author Boutopoulos, C en
dc.contributor.author Zergioti, I en
dc.contributor.author Chatzandroulis, S en
dc.date.accessioned 2014-03-01T11:45:10Z
dc.date.available 2014-03-01T11:45:10Z
dc.date.issued 2011 en
dc.identifier.issn 0956-5663 en
dc.identifier.uri http://hdl.handle.net/123456789/37263
dc.subject Biomolecular interactions en
dc.subject Biosensors en
dc.subject Capacitive detection en
dc.subject Micro-electrodes en
dc.subject Micro-membranes en
dc.subject.classification Biophysics en
dc.subject.classification Biotechnology & Applied Microbiology en
dc.subject.classification Chemistry, Analytical en
dc.subject.classification Electrochemistry en
dc.subject.classification Nanoscience & Nanotechnology en
dc.subject.other Advanced diagnostics en
dc.subject.other Antigen-antibody binding en
dc.subject.other Biological applications en
dc.subject.other Biological sensing en
dc.subject.other Biomolecular interactions en
dc.subject.other Capacitive biosensors en
dc.subject.other Capacitive detection en
dc.subject.other Classical methods en
dc.subject.other DNA hybridization en
dc.subject.other Early detection en
dc.subject.other Label free en
dc.subject.other Micro-membranes en
dc.subject.other Operation principles en
dc.subject.other Personalized medicines en
dc.subject.other Portable device en
dc.subject.other Surface stress en
dc.subject.other Biosensors en
dc.subject.other Electrodes en
dc.subject.other Microsystems en
dc.subject.other artificial membrane en
dc.subject.other biosensor en
dc.subject.other capacitive membrane en
dc.subject.other capacitive microsystem en
dc.subject.other DNA determination en
dc.subject.other DNA microarray en
dc.subject.other electric capacitance en
dc.subject.other electrode en
dc.subject.other equipment design en
dc.subject.other interdigitated electrode en
dc.subject.other microelectrode en
dc.subject.other microelectromechanical system en
dc.subject.other microtechnology en
dc.subject.other molecular interaction en
dc.subject.other nonhuman en
dc.subject.other review en
dc.subject.other solution and solubility en
dc.subject.other surface stress en
dc.subject.other Biosensing Techniques en
dc.subject.other Electric Capacitance en
dc.subject.other Humans en
dc.subject.other Miniaturization en
dc.title Capacitive microsystems for biological sensing en
heal.type other en
heal.identifier.primary 10.1016/j.bios.2011.05.047 en
heal.identifier.secondary http://dx.doi.org/10.1016/j.bios.2011.05.047 en
heal.language English en
heal.publicationDate 2011 en
heal.abstract The growing interest in personalized medicine leads to the need for fast, cheap and portable devices that reveal the genetic profile easily and accurately. To this direction, several ideas to avoid the classical methods of diagnosis and treatment through miniaturized and label-free systems have emerged. Capacitive biosensors address these requirements and thus have the perspective to be used in advanced diagnostic devices that promise early detection of potential fatal conditions. The operation principles, as well as the design and fabrication of several capacitive microsystems for the detection of biomolecular interactions are presented in this review. These systems are micro-membranes based on surface stress changes, interdigitated micro-electrodes and electrode-solution interfaces. Their applications extend to DNA hybridization, protein-ligand binding, antigen-antibody binding, etc. Finally, the limitations and prospects of capacitive microsystems in biological applications are discussed. (C) 2011 Elsevier B.V. All rights reserved. en
heal.journalName Biosensors and Bioelectronics en
dc.identifier.doi 10.1016/j.bios.2011.05.047 en
dc.identifier.isi ISI:000295953300001 en
dc.identifier.volume 27 en
dc.identifier.issue 1 en
dc.identifier.spage 1 en
dc.identifier.epage 11 en

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