From chemistry of DNA damage to repair and biological significance. Comprehending the future

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dc.contributor.author Georgakilas, AG en
dc.date.accessioned 2014-03-01T11:45:11Z
dc.date.available 2014-03-01T11:45:11Z
dc.date.issued 2011 en
dc.identifier.issn 0027-5107 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/37272
dc.subject Biomarkers en
dc.subject DNA damage en
dc.subject DNA repair en
dc.subject Oxidative stress en
dc.subject Pathogenesis en
dc.subject.classification Biotechnology & Applied Microbiology en
dc.subject.classification Genetics & Heredity en
dc.subject.classification Toxicology en
dc.subject.other DNA en
dc.subject.other reactive oxygen metabolite en
dc.subject.other Alzheimer disease en
dc.subject.other chromosomal instability en
dc.subject.other chromosome aberration en
dc.subject.other disease predisposition en
dc.subject.other DNA cross linking en
dc.subject.other DNA damage en
dc.subject.other DNA repair en
dc.subject.other editorial en
dc.subject.other gene mutation en
dc.subject.other heart disease en
dc.subject.other human en
dc.subject.other inflammation en
dc.subject.other ionizing radiation en
dc.subject.other malignant neoplastic disease en
dc.subject.other nonhuman en
dc.subject.other oxidative stress en
dc.subject.other priority journal en
dc.subject.other risk factor en
dc.subject.other temperature en
dc.subject.other DNA Damage en
dc.subject.other DNA Repair en
dc.subject.other Humans en
dc.subject.other Oxidative Stress en
dc.title From chemistry of DNA damage to repair and biological significance. Comprehending the future en
heal.type other en
heal.identifier.primary 10.1016/j.mrfmmm.2011.04.001 en
heal.identifier.secondary http://dx.doi.org/10.1016/j.mrfmmm.2011.04.001 en
heal.language English en
heal.publicationDate 2011 en
heal.abstract Knowledge of the chemistry behind induction of DNA damage and processing mechanisms is considered very important not only for the understanding of the biological significance but also for clinical applications. In this Special Issue, we have compiled a number of succinct reviews and original research articles, by top experts in their fields. The articles discuss and/or explore the current status of knowledge and new advances in the chemical and molecular pathways related to the induction of high oxidative stress, DNA damage and its repair in human cells and tissues. Experimental and theoretical insights are provided of how the DNA repair processes maybe modulated by gene mutations and other factors like temperature and radiation quality. (C) 2011 Elsevier B.V. All rights reserved. en
heal.publisher ELSEVIER SCIENCE BV en
heal.journalName Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis en
dc.identifier.doi 10.1016/j.mrfmmm.2011.04.001 en
dc.identifier.isi ISI:000291914700001 en
dc.identifier.volume 711 en
dc.identifier.issue 1-2 en
dc.identifier.spage 1 en
dc.identifier.epage 2 en

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