From chemistry of DNA damage to repair and biological significance. Comprehending the future

Georgakilas, AG

dc.contributor.author	Georgakilas, AG	en
dc.date.accessioned	2014-03-01T11:45:11Z
dc.date.available	2014-03-01T11:45:11Z
dc.date.issued	2011	en
dc.identifier.issn	0027-5107	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/37272
dc.subject	Biomarkers	en
dc.subject	DNA damage	en
dc.subject	DNA repair	en
dc.subject	Oxidative stress	en
dc.subject	Pathogenesis	en
dc.subject.classification	Biotechnology & Applied Microbiology	en
dc.subject.classification	Genetics & Heredity	en
dc.subject.classification	Toxicology	en
dc.subject.other	DNA	en
dc.subject.other	reactive oxygen metabolite	en
dc.subject.other	Alzheimer disease	en
dc.subject.other	chromosomal instability	en
dc.subject.other	chromosome aberration	en
dc.subject.other	disease predisposition	en
dc.subject.other	DNA cross linking	en
dc.subject.other	DNA damage	en
dc.subject.other	DNA repair	en
dc.subject.other	editorial	en
dc.subject.other	gene mutation	en
dc.subject.other	heart disease	en
dc.subject.other	human	en
dc.subject.other	inflammation	en
dc.subject.other	ionizing radiation	en
dc.subject.other	malignant neoplastic disease	en
dc.subject.other	nonhuman	en
dc.subject.other	oxidative stress	en
dc.subject.other	priority journal	en
dc.subject.other	risk factor	en
dc.subject.other	temperature	en
dc.subject.other	DNA Damage	en
dc.subject.other	DNA Repair	en
dc.subject.other	Humans	en
dc.subject.other	Oxidative Stress	en
dc.title	From chemistry of DNA damage to repair and biological significance. Comprehending the future	en
heal.type	other	en
heal.identifier.primary	10.1016/j.mrfmmm.2011.04.001	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.mrfmmm.2011.04.001	en
heal.language	English	en
heal.publicationDate	2011	en
heal.abstract	Knowledge of the chemistry behind induction of DNA damage and processing mechanisms is considered very important not only for the understanding of the biological significance but also for clinical applications. In this Special Issue, we have compiled a number of succinct reviews and original research articles, by top experts in their fields. The articles discuss and/or explore the current status of knowledge and new advances in the chemical and molecular pathways related to the induction of high oxidative stress, DNA damage and its repair in human cells and tissues. Experimental and theoretical insights are provided of how the DNA repair processes maybe modulated by gene mutations and other factors like temperature and radiation quality. (C) 2011 Elsevier B.V. All rights reserved.	en
heal.publisher	ELSEVIER SCIENCE BV	en
heal.journalName	Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis	en
dc.identifier.doi	10.1016/j.mrfmmm.2011.04.001	en
dc.identifier.isi	ISI:000291914700001	en
dc.identifier.volume	711	en
dc.identifier.issue	1-2	en
dc.identifier.spage	1	en
dc.identifier.epage	2	en