Anaemia in systemic lupus erythematosus: from pathophysiology to clinical assessment

Giannouli, S; Voulgarelis, M; Ziakas, PD; Tzioufas, AG

dc.contributor.author	Giannouli, S	en
dc.contributor.author	Voulgarelis, M	en
dc.contributor.author	Ziakas, PD	en
dc.contributor.author	Tzioufas, AG	en
dc.date.accessioned	2014-03-01T11:46:11Z
dc.date.available	2014-03-01T11:46:11Z
dc.date.issued	2006	en
dc.identifier.issn	0003-4967	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/37732
dc.subject.classification	Rheumatology	en
dc.subject.other	RED-CELL APLASIA	en
dc.subject.other	AUTOIMMUNE HEMOLYTIC-ANEMIA	en
dc.subject.other	RECOMBINANT-HUMAN-ERYTHROPOIETIN	en
dc.subject.other	TREATED HUMAN ERYTHROCYTES	en
dc.subject.other	MARROW CD34(+) CELLS	en
dc.subject.other	ANTICARDIOLIPIN ANTIBODIES	en
dc.subject.other	ANTIPHOSPHOLIPID ANTIBODIES	en
dc.subject.other	THROMBOCYTOPENIC PURPURA	en
dc.subject.other	PERNICIOUS-ANEMIA	en
dc.subject.other	DISEASE-ACTIVITY	en
dc.title	Anaemia in systemic lupus erythematosus: from pathophysiology to clinical assessment	en
heal.type	other	en
heal.language	English	en
heal.publicationDate	2006	en
heal.abstract	Haematological abnormalities are common in systemic lupus erythematosus. Anaemia is found in about 50% of patients, with anaemia of chronic disease being the most common form. Impaired erythropoietin response and presence of antibodies against erythropoietin may contribute to the pathogenesis of this type of anaemia. Patients with autoimmune haemolytic anaemia usually belong to a distinct category, which is associated with anticardiolipin antibodies, thrombosis, thrombocytopenia, and renal disease, often in the context of secondary antiphospholipid syndrome. Autoantibodies, T lymphocytes, and deregulation of the cytokine network can affect bone marrow erythropoiesis, leading to anaemia.	en
heal.publisher	B M J PUBLISHING GROUP	en
heal.journalName	ANNALS OF THE RHEUMATIC DISEASES	en
dc.identifier.isi	ISI:000234588900002	en
dc.identifier.volume	65	en
dc.identifier.issue	2	en
dc.identifier.spage	144	en
dc.identifier.epage	148	en