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Anaemia in systemic lupus erythematosus: from pathophysiology to clinical assessment

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dc.contributor.author Giannouli, S en
dc.contributor.author Voulgarelis, M en
dc.contributor.author Ziakas, PD en
dc.contributor.author Tzioufas, AG en
dc.date.accessioned 2014-03-01T11:46:11Z
dc.date.available 2014-03-01T11:46:11Z
dc.date.issued 2006 en
dc.identifier.issn 0003-4967 en
dc.identifier.uri https://dspace.lib.ntua.gr/xmlui/handle/123456789/37732
dc.subject.classification Rheumatology en
dc.subject.other RED-CELL APLASIA en
dc.subject.other AUTOIMMUNE HEMOLYTIC-ANEMIA en
dc.subject.other RECOMBINANT-HUMAN-ERYTHROPOIETIN en
dc.subject.other TREATED HUMAN ERYTHROCYTES en
dc.subject.other MARROW CD34(+) CELLS en
dc.subject.other ANTICARDIOLIPIN ANTIBODIES en
dc.subject.other ANTIPHOSPHOLIPID ANTIBODIES en
dc.subject.other THROMBOCYTOPENIC PURPURA en
dc.subject.other PERNICIOUS-ANEMIA en
dc.subject.other DISEASE-ACTIVITY en
dc.title Anaemia in systemic lupus erythematosus: from pathophysiology to clinical assessment en
heal.type other en
heal.language English en
heal.publicationDate 2006 en
heal.abstract Haematological abnormalities are common in systemic lupus erythematosus. Anaemia is found in about 50% of patients, with anaemia of chronic disease being the most common form. Impaired erythropoietin response and presence of antibodies against erythropoietin may contribute to the pathogenesis of this type of anaemia. Patients with autoimmune haemolytic anaemia usually belong to a distinct category, which is associated with anticardiolipin antibodies, thrombosis, thrombocytopenia, and renal disease, often in the context of secondary antiphospholipid syndrome. Autoantibodies, T lymphocytes, and deregulation of the cytokine network can affect bone marrow erythropoiesis, leading to anaemia. en
heal.publisher B M J PUBLISHING GROUP en
heal.journalName ANNALS OF THE RHEUMATIC DISEASES en
dc.identifier.isi ISI:000234588900002 en
dc.identifier.volume 65 en
dc.identifier.issue 2 en
dc.identifier.spage 144 en
dc.identifier.epage 148 en


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