Structural analysis of biodegradable low-molecular mass copolyesters based on glycolic acid, adipic acid and 1,4 butanediol and correlation with their hydrolytic degradation

Soulis, S; Triantou, D; Weidner, S; Falkenhagen, J; Simitzis, J

dc.contributor.author	Soulis, S	en
dc.contributor.author	Triantou, D	en
dc.contributor.author	Weidner, S	en
dc.contributor.author	Falkenhagen, J	en
dc.contributor.author	Simitzis, J	en
dc.date.accessioned	2014-03-01T11:47:18Z
dc.date.available	2014-03-01T11:47:18Z
dc.date.issued	2012	en
dc.identifier.issn	01413910	en
dc.identifier.uri	https://dspace.lib.ntua.gr/xmlui/handle/123456789/38117
dc.subject	Biodegradable	en
dc.subject	Biopolymers	en
dc.subject	Ft-IR	en
dc.subject	Hydrolytic degradation	en
dc.subject	Matrix-assisted laser desorption/ionization-time-of-flight-mass spectrometry (MALDI-TOF MS)	en
dc.title	Structural analysis of biodegradable low-molecular mass copolyesters based on glycolic acid, adipic acid and 1,4 butanediol and correlation with their hydrolytic degradation	en
heal.type	other	en
heal.identifier.primary	10.1016/j.polymdegradstab.2012.09.002	en
heal.identifier.secondary	http://dx.doi.org/10.1016/j.polymdegradstab.2012.09.002	en
heal.publicationDate	2012	en
heal.abstract	Copolyesters of glycolic acid combined with adipic acid and 1,4 butanediol were synthesized, their in vitro hydrolytic degradation was studied and correlated with their structure. The hydrolytic degradation of the copolyesters was directly related with the degree of crystallinity and the diameter of the crystallites. It was found that glycolate units disturb the ordering of the butylene adipate units, which results in a decrease of the crystallinity. By comparing the hydrolysis parameters of synthesized copolyesters with those of similar aliphatic copolyesters a hydrolysis mechanism was proposed. According to this mechanism, the degradation takes place not only by the loss of end units, but also through the removal of larger segments. MALDI-TOF MS data showed that the possibility of a copolyester macromolecule forming cyclic structures correlates with the arrangement of ester groups in the macromolecules and the structure of the linear segments. © 2012 Elsevier Ltd. All rights reserved.	en
heal.journalName	Polymer Degradation and Stability	en
dc.identifier.doi	10.1016/j.polymdegradstab.2012.09.002	en